Browsing Faculté de médecine vétérinaire – Travaux et publications by Title
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Actinobacillus pleuropneumoniae (App) culture supernatant antiviral effect against porcine reproductive and respiratory syndrome virus (PRRSV) occurs prior to the viral genome replication and transcription through actin depolymerization
(Microbiology Society, 2018-01-02)PURPOSE: Recently, the strong antiviral activity of an Actinobacillus pleuropneumoniae (App) culture supernatant against porcine reproductive and respiratory syndrome virus (PRRSV) was discovered. Following this finding, the objective of the present ... -
Actinobacillus pleuropneumoniae induces SJPL cell cycle arrest in G2/M-phase and inhibits porcine reproductive and respiratory syndrome virus replication
(2015-12)Background: Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most important pathogens in the swine industry and causes important economic losses. No effective antiviral drugs against it are commercially available. We recently ... -
Actinobacillus pleuropneumoniae Possesses an Antiviral Activity against Porcine Reproductive and Respiratory Syndrome Virus
(2014-05)Pigs are often colonized by more than one bacterial and/or viral species during respiratory tract infections. This phenomenon is known as the porcine respiratory disease complex (PRDC). Actinobacillus pleuropneumoniae (App) and porcine reproductive ... -
The administration of diets contaminated with low to intermediate doses of deoxynivalenol and supplemented with antioxidants and binding agents slightly affects the growth, antioxidant status and vaccine response in weanling pigs
(Oxford University Press, 2021-08-18)This study aimed to evaluate the impact of grading levels of deoxynivalenol (DON) in the diet of weaned pigs, as well as the effects of a supplementation with antioxidants (AOX), hydrated sodium calcium aluminosilicates (HSCAS) and their combination ... -
Alternative codon usage of PRRS virus ORF5 gene increases eucaryotic expression of GP5 glycoprotein and improves immune response in challenged pigs
(2005-07)Pigs exposed to GP5 protein of PRRSV by means of DNA immunization develop specific neutralizing and protecting antibodies. Herein, we report on the consequences of codon bias, and on the favorable outcome of the systematic replacement of native codons ... -
Analysis of whole-genome sequences of infectious laryngotracheitis virus isolates from poultry flocks in Canada : evidence of recombination
(MDPI, 2020-11-12)Infectious laryngotracheitis virus (ILTV) is a herpes virus that causes an acute respiratory disease of poultry known as infectious laryngotracheitis (ILT). Chicken embryo origin (CEO) and tissue culture origin (TCO) live attenuated vaccines are routinely ... -
Anandamide modulates thermal avoidance in caenorhabditis elegans through vanilloid and cannabinoid receptor interplay
(Springer, 2024-03-27)Understanding the endocannabinoid system in C. elegans may offer insights into basic biological processes and potential therapeutic targets for managing pain and inflammation in human. It is well established that anandamide modulates pain perception ... -
Anatomic and molecular characterization of the 1 endocrine pancreas of a teleostean fish: Atlantic wolffish (Anarhichas lupus)
(2015-01)Background: The biologic attributes of the endocrine pancreas and the comparative endocrinology of islet amyloid polypeptide (IAPP) of fish are not well described in the literature. This study describes the endocrine pancreas of one teleostean fish. ... -
Antinociceptive activity of vanilloids in caenorhabditis elegans is mediated by the desensitization of the TRPV channel OCR-2 and specific signal transduction pathways
(Springer, 2023-02-03)Vanilloids, including capsaicin and eugenol, are ligands of transient receptor potential channel vanilloid subfamily member 1 (TRPV1). Prolonged treatment with vanilloids triggered the desensitization of TRPV1, leading to analgesic or antinociceptive ... -
Assessment of meat authenticity using bioinformatics, targeted peptide biomarkers and high-resolution mass spectrometry
(2015-10-01)In recent years, we observed a significant increase of food fraud ranging from false label claims to the use of additives and fillers to increase profitability. Recently in 2013, horse and pig DNA were detected in beef products sold from several ... -
Assessment of Tandem Mass Spectrometry and High Resolution Mass Spectrometry for the Analysis of Bupivacaine in Plasma
(2015-11-01)Triple quadrupole mass spectrometers coupled with high performance liquid chromatography are workhorses in quantitative bioanalyses. It provides substantial benefits including reproducibility, sensitivity and selectivity for trace analysis. Selected ... -
Bilan 2020 : identification des pathogènes aviaires au Québec grâce à l’utilisation de tests moléculaires
(Ordre des médecins vétérinaires du Québec, 2021) -
Bird species involved in west nile virus epidemiological cycle in southern Québec
(MDPI, 2020-06-23)Despite many studies on West Nile Virus (WNV) in the US, including the reservoir role of bird species and the summer shifts of the Culex mosquito, feeding from birds to mammals, there have been few equivalent studies in the neighboring regions of ... -
Cannabidiol and tetrahydrocannabinol antinociceptive activity is mediated by distinct receptors in caenorhabditis elegans
(Springer, 2023-11-22)Cannabis has gained popularity in recent years as a substitute treatment for pain following the risks of typical treatments uncovered by the opioid crisis. The active ingredients frequently associated with pain-relieving effects are the phytocannabinoids ... -
Cannflavins isolated from cannabis sativa impede caenorhabditis elegans response to noxious heat
(Springer, 2023-07-22)Cannflavins, flavonoids abundantly present in Cannabis sativa, possess a distinct chemical structure comprising a vanillyl group. Notably, the capsaicin structure also contains a vanillyl group, which is considered essential for interacting with the ... -
Capsaicin and Its analogues impede nocifensive response of caenorhabditis elegans to noxious heat
(2020-05-05)Capsaicin is the most abundant pungent molecule identifed in red chili peppers, and it is widely used for food favoring, in pepper spray for self-defense devices and recently in ointments for the relief of neuropathic pain. Capsaicin and several other ... -
Capsular sialic acid of Streptococcus suis serotype 2 binds to swine influenza virus and enhances bacterial interactions with virus-infected tracheal epithelial cells
(2013-12)Streptococcus suis serotype 2 is an important swine bacterial pathogen, and it is also an emerging zoonotic agent. It is unknown how S. suis virulent strains, which are usually found in low quantities in pig tonsils, manage to cross the first host ... -
Case Report: Esophagitis and pharyngitis associated with avian infectious laryngotracheitis in backyard chickens: 2 cases
(2017-06)Infectious laryngotracheitis (ILT) is a contagious viral respiratory disease of great economic importance for the global poultry industry caused by Gallid herpesvirus 1 (GaHV-1). Lesions of the upper digestive tract caused by this virus have not been ... -
Characterisation of InlA truncation in Listeria monocytogenes isolates from farm animals and human cases in the province of Quebec
(2017-06)The introduction of Listeria monocytogenes into the food production chain is a concern, with numerous grouped cases of listeriosis associated with milk-derived or pork-derived products have been documented. Management of this zoonotic pathogen considers ... -
Characterization of a Canadian mink H3N2 influenza A virus isolate genetically related to triple reassortant swine influenza virus
(2009-03)In 2007, an H3N2 influenza A virus was isolated from Canadian mink. This virus was found to be phylogenetically related to a triple reassortant influenza virus which emerged in Canadian swine in 2005, but it is antigenically distinct. The transmission ... -
Characterization of Endoproteolytic Processing of Dynorphins by Proprotein Convertases using Mouse Spinal Cord S9 Fractions and Mass Spectrometry
(2016-06-01)Dynorphins are important neuropeptides with a central role in nociception and pain alleviation. Many mechanisms regulate endogenous dynorphin concentrations, including proteolysis. Proprotein convertases (PCs) are widely expressed in the central nervous ... -
Chicken astrovirus (CAstV) molecular studies reveal evidence of multiple past recombination events in sequences originated from clinical samples of white chick syndrome (WCS) in Western Canada
(MDPI, 2020-09-28)In this study, we aimed to molecularly characterize 14 whole genome sequences of chicken astrovirus (CAstV) isolated from samples obtained from white chick syndrome (WCS) outbreaks in Western Canada during the period of 2014–2019. Genome sequence ... -
Chicken Caecal Microbiome Modifications Induced by Campylobacter jejuni Colonization and by a Non-Antibiotic Feed Additive
(2015-07)Campylobacter jejuni is an important zoonotic foodborne pathogen causing acute gastroenteritis in humans. Chickens are often colonized at very high numbers by C. jejuni, up to 109 CFU per gram of caecal content, with no detrimental effects on their ... -
Coding-complete genome sequence of a Falcon aviadenovirus A strain associated with necrotizing hepatitis in an American Kestrel (Falco sparverius)
(American Society for Microbiology, 2022-03-17)A necropsy was performed on an American kestrel (Falco sparverius) with necrotizing hepatitis associated with inclusion bodies, suggesting an adenovirus infection. A next-generation sequencing assay was conducted on the liver, and the coding-complete ... -
Coinfections and their molecular consequences in the porcine respiratory tract
(BMC, 2020-06-16)Understudied, coinfections are more frequent in pig farms than single infections. In pigs, the term “Porcine Respiratory Disease Complex” (PRDC) is often used to describe coinfections involving viruses such as swine Influenza A Virus (swIAV), Porcine ... -
Comparative full genome sequence analysis of wild-type and chicken embryo origin vaccine-like infectious laryngotracheitis virus field isolates from Canada
(Elsevier, 2022-08-14)Infectious laryngotracheitis (ILT), caused by infectious laryngotracheitis virus (ILTV), occurs sporadically in poultry flocks in Canada. Live attenuated chicken embryo origin (CEO) vaccines are being used routinely to prevent and control ILTV infections. ... -
Comparison of primary virus isolation in pulmonary alveolar macrophages and four different continuous cell lines for type 1 and type 2 porcine reproductive and respiratory syndrome virus
(MDPI, 2021-06-03)Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) has a highly restricted cellular tropism. In vivo, the virus primarily infects tissue-specific macrophages in the nose, lungs, tonsils, and pharyngeal lymphoid tissues. In vitro however, the ... -
Complete genome sequence of a Circovirus pigeon strain in lymphocyte-depleted bursa of Fabricius of a Common Raven (Corvus corax)
(Elsevier, 2024-08-30)A necropsy was performed on a Common Raven (Corvus corax) presenting an opportunistic fungal respiratory infection and a bursal lymphoid depletion with inclusion bodies, suggestive of a circovirus infection. High-throughput sequencing of circular ... -
Correlation between coral lesions and skin hyperpigmentation in reef fish of the Southwest coast of Grenada
(University of Puerto Rico (Mayagüez Campus), 2024-09-11)Marine ecosystems rely on hard corals. Since 2014, a rapidly spreading disease causing stony coral tissue loss disease (SCTLD) has devastated coral reefs in the Caribbean. In 2019, corals exhibiting necrotic lesions compatible with SCTLD were documented ... -
Deoxynivalenol (DON) naturally contaminated feed impairs the immune response induced by porcine reproductive and respiratory syndrome virus (PRRSV) live attenuated vaccine
(2015-07-31)Cereal commodities are frequently contaminated with mycotoxins produced by the secondary metabolism of fungal infection. Among these contaminants, deoxynivalenol (DON), also known as vomitoxin, is the most prevalent type B trichothecene mycotoxin ... -
Development and use of a multiplex real-time quantitative polymerase chain reaction assay for detection and differentiation of Porcine circovirus-2 genotypes 2a and 2b in an epidemiological survey
(2008-09)By the end of 2004, the Canadian swine population had experienced a severe 2 increase in the incidence of Porcine circovirus-associated disease (PCVAD), a problem that was 3 associated with the emergence of a new Porcine circovirus-2 genotype (PCV-2b), ... -
Diagnosing intramammary infection : a scoping review and meta-analysis on frequency and udder-health relevance of microorganism species retrieved in bovine milk samples
(2021-02-05)The scoping review methodology protocol. There are two parts described: scoping review procedure and details on meta-analysis. -
Diagnosis and surgical management of cholecystolithiasis in two adult inland beardeddragons (pogona vitticeps)
(Association of Reptile and Amphibian Veterinarians, 2021-05-06)Two male inland bearded dragons (Pogona vitticeps) of 5 and 6 yr of age were presented for anorexia with and without lethargy, respectively. In both cases, a firm, spherical, and mobile mass, measuring 2 cm in diameter, was palpated in the cranio-medial ... -
Distinct miRNA profile of cellular and extracellular vesicles released from chicken tracheal cells following avian influenza virus infection
(MDPI, 2020-08-05)Innate responses provide the first line of defense against viral infections, including the influenza virus at mucosal surfaces. Communication and interaction between different host cells at the early stage of viral infections determine the quality ... -
Dual infections of CD163 expressing NPTr epithelial cells with influenza A virus and PRRSV
(2017-08)In the pig, respiratory co-infections involving various pathogens are far more frequent than single infections. Amongst respiratory viruses, swine influenza type A virus (swIAV) and porcine reproductive and respiratory syndrome virus (PRRSV) are ... -
DUSP1 mRNA modulation during porcine circovirus type 2 and porcine reproductive and respiratory syndrome virus co-infection regulates viruses replication
(Elsevier, 2023-12-01)The effects of porcine circovirus type 2b (PCV2b) and porcine reproductive and respiratory syndrome virus (PRRSV) co-infection in epithelial cells of the swine respiratory tract is unknown. In the present study, the newborn pig trachea cell line ... -
Dynamics of viral distribution in a defined swine production network using enteric viruses as molecular markers
(2017-02)Modern swine production systems represent complex and dynamic networks involving numerous stakeholders. For instance, livestock transporters carry live animals between fattening sites, abattoirs, and other premises on a daily basis. This interconnected ... -
Effect of deoxynivalenol (DON) mycotoxin on in vivo and in vitro porcine circovirus type 2 infections
(2015-04)Deoxynivalenol (DON) is a mycotoxin produced by Fusarium spp and is a common contaminant of grains in North America. Among farm animals, swine are the most susceptible to DON because it markedly reduces feed intake and decreases weight gain. Porcine ... -
Emergence of a New Swine H3N2 and Pandemic (H1N1) 2009 Influenza A Virus Reassortant in Two Canadian Animal Populations, Mink and Swine
(2011-12)A swine H3N2 (swH3N2) and pandemic (H1N1) 2009 (pH1N1) influenza A virus reassortant (swH3N2/ pH1N1) was detected in Canadian swine at the end of 2010. Simultaneously, a similar virus was also detected in Canadian mink based on partial viral genome ... -
Emergence of a new type of porcine circovirus (PCV) in swine: a type 1 and type 2 PCV recombinant
(2010-07)In late September 2008, tissue samples from piglets experiencing an acute outbreak of porcine reproductive and respiratory syndrome (PRRS) were submitted to the Veterinary diagnostic service of the University of Montreal. Several diagnostic assays were ... -
The emergence of porcine circovirus 2b genotype (PCV-2b) in swine in Canada
(2007-08-01)Since late 2004, the swine industry in the province of Quebec has experienced a significant increase in death rate related to postweaning multisystemic wasting syndrome (PMWS). To explain this phenomenon, 2 hypotheses were formulated: 1) the presence ... -
Epidemiological study of Coxiella burnetii in dairy cattle and small ruminants in Québec, Canada
(Elsevier, 2021-04-25)The bacterium Coxiella burnetii (C. burnetii) can infect a wide range of animals, most notably ruminants where it causes mainly asymptomatic infections and, when clinical, it is associated with reproductive disorders such as abortion. It is also the ... -
Establishment of preliminary reference intervals and cytochemical staining of blood cells in big-bellied seahorses (Hippocampus abdominalis)
(Wiley, 2023-03-10)AbstractBackground: Despite their popularity, hematology reference intervals (RIs) have not been established in big- bellied seahorses (Hippocampus abdominalis).Objective: The objectives of this study were to establish hematologic RIs to compare values ... -
Eucaryotic Expression of the Nucleocapsid Protein Gene of Porcine Circovirus Type 2 and Use of the Protein in an Indirect Immunofluorescence Assay for Serological Diagnosis of Postweaning Multisystemic Wasting Syndrome in Pigs
(2004-07)The purpose of this study was to develop a sensitive, rapid, and inexpensive immunofluorescence assay (IFA) using a recombinant porcine circovirus type 2 (PCV2) nucleocapsid protein for the serological detection of PCV2-specific antibodies in pig sera. ... -
Eugenol and other vanilloids hamper caenorhabditis elegans response to noxious heat
(Springer, 2020-10-29)Eugenol, a known vanilloid, was frequently used in dentistry as a local analgesic in addition, antibacterial and neuroprotective effects were also reported. Eugenol, capsaicin and many vanilloids are interacting with the transient receptor potential ... -
Euthanasia and management of downer cows on farm : online survey
(2019-03)The goal of this survey is to make an inventory of the practices usedon farm to euthanize and manage downers and identify challenges producers face. Our aim is to assemble an overall and representative picture of current practices in order to better ... -
Euthanasie et gestion des bovins non-ambulatoires : sondage électronique
(2019-03)Ce sondage a comme objectif de répertorier les pratiques utilisées pour l’euthanasie et la gestion des bovins laitiers non-ambulatoires à la ferme ainsi que les défis rencontrés par les producteurs. Nous voulons dresser un portrait global et représentatif ... -
Evaluation of multiple reaction monitoring cubed for the analysis of tachykinin related peptides in rat spinal cord using a hybrid triple quadrupole–linear ion trap mass spectrometer
(2014-02)Targeted peptide methods generally use HPLC-MS/MRM approaches. Although dependent on the instrumental resolution, interferences may occur while performing analysis of complex biological matrices. HPLC-MS/MRM3 is a technique, which provides a significantly ... -
Evaluation of recombinant Herpesvirus of Turkey Laryngotracheitis (rHVT-LT) Vaccine against Genotype VI Canadian Wild-Type Infectious Laryngotracheitis Virus (ILTV) Infection
(MDPI, 2021-12-03)In Alberta, infectious laryngotracheitis virus (ILTV) infection is endemic in backyard poultry flocks; however, outbreaks are only sporadically observed in commercial flocks. In addition to ILTV vaccine revertant strains, wild-type strains are among ... -
Evaluation of the safety of multiple intramuscular doses of ketoprofen in bearded dragons (Pogona vitticeps)
(Association of reptilian and amphibian veterinarians, 2022-05-30)Cyclooxygenase (COX) 1 has been shown to increase significantly in inflamed ophidian skin and chelonian muscles. Nonselective COX-1 and COX-2 inhibitors, such as ketoprofen, could therefore reduce inflammation more effectively than preferential COX-2 ... -
Evaluation of the safety of multiple intramuscular doses of ketoprofen in bearded dragons (Pogona vitticeps)
(Association of reptilian and amphibian veterinarians, 2022-05-30)Cyclooxygenase (COX) 1 has been shown to increase significantly in inflamed ophidian skin and chelonian muscles. Nonselective COX-1 and COX-2 inhibitors, such as ketoprofen, could therefore reduce inflammation more effectively than preferential COX-2 ... -
Exposure of feral swine (Sus scrofa) in the United States to selected pathogens
(2015-01)Les porcs sauvages (Sus scrofa) sont largement distribués aux États-Unis. En 2011 et 2012, aux États-Unis des échantillons de sérum et d’amygdales furent obtenus de 162 et 37 porcs sauvages, respectivement, afin d’évaluer l’exposition à d’importants ... -
Extended-spectrum β-lactamase, carbapenemase, and the mcr-1 gene: Is there a historical link?
(2017-03-30)The plasmid mediated mcr-1 gene encoding for Enterobacteriaceae colistin resistance has been recently identified across five continents. The objective of the present study was to trace historical events concerning the discovery and emergence of the ... -
Extensive characterization of Campylobacter jejuni chicken isolates to uncover genes involved in the ability to compete for gut colonization
(2015-05)Background: Campylobacter jejuni is responsible for human foodborne enteritis. This bacterium is a remarkable colonizer of the chicken gut, with some strains outcompeting others for colonization. To better understand this phenomenon, the objective ...
