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  • Active nuclear import and cytoplasmic retention of activation-induced deaminase 

    Patenaude, Anne-Marie; Orthwein, Alexandre; Hu, Yi; Campo, Vanina A.; Kavli, Bodil; Buschiazzo, Alejandro; Di Noia, Javier M. (2009)
    The enzyme activation-induced deaminase (AID) triggers antibody diversification in B cells by catalyzing deamination and consequently mutation of immunoglobulin genes. To minimize off-target deamination, AID is restrained by several regulatory mechanisms ...