Browsing Titles index "Active nuclear import and cytoplasmic retention of activation-induced deaminase"

Now showing items 1-1 of 1

  • Active nuclear import and cytoplasmic retention of activation-induced deaminase 

    Patenaude, Anne-Marie; Orthwein, Alexandre; Hu, Yi; Campo, Vanina A.; Kavli, Bodil; Buschiazzo, Alejandro; Di Noia, Javier Marcelo (2009)
    The enzyme activation-induced deaminase (AID) triggers antibody diversification in B cells by catalyzing deamination and consequently mutation of immunoglobulin genes. To minimize off-target deamination, AID is restrained by several regulatory mechanisms ...