Browsing Titles index "Active nuclear import and cytoplasmic retention of activation-induced deaminase"
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Active nuclear import and cytoplasmic retention of activation-induced deaminase
(2009)The enzyme activation-induced deaminase (AID) triggers antibody diversification in B cells by catalyzing deamination and consequently mutation of immunoglobulin genes. To minimize off-target deamination, AID is restrained by several regulatory mechanisms ...