Now showing items 1-20 of 271

  • A 12-week open-label, multicenter study evaluating the safety and patient-reported efficacy of sodium oxybate in patients with narcolepsy and cataplexy 

    Mamelak, Mortimer; Swick, Todd; Emsellem, Helene; Montplaisir, Jacques-Yves; Lai, Chinglin; Black, Jed (Elsevier, 2015)
    Objective: This study aimed to evaluate safety and efficacy of sodium oxybate (SXB) titrated to effect. Methods: SXB-naive patients who had participated in a randomized SXB clinical trial and had not been titrated to adequate clinical effect were ...
  • 3D Cohort Study : The Integrated Research Network in Perinatology of Quebec and Eastern Ontario 

    Fraser, William; Shapiro, Gabriel; Dubois, Lise; Pasquier, Jean-Charles; Julien, Pierre; Berard, Anick; Muckle, Gina; Trasler, Jacquetta; Tremblay, Richard Ernest; Abenhaim, Haim; Welt, Michel; Bissonnette, François; Bédard, Marie-Josée; Bujold, Emmanuel; Gagnon, Robert; Michaud, Jacques; Girard, Isabelle; Moutquin, Jean-Marie; Marc, Isabelle; Monnier, Patricia; Luo, Zhong-Cheng; 3D Study Group; Séguin, Jean; Audibert, François (Wiley, 2016)
    Background: The 3D Cohort Study (Design, Develop, Discover) was established to help bridge knowledge gaps about the links between various adverse exposures during pregnancy with birth outcomes and later health outcomes in children. Methods: Pregnant ...
  • 3D registration of MR and X-ray spine images using an articulated model 

    Harmouche, Rola; Cheriet, Farida; Labelle, Hubert; Dansereau, Jean (2012-07)
    Présentation: Cet article a été publié dans le journal : Computerised medical imaging and graphics (CMIG). Le but de cet article est de recaler les vertèbres extraites à partir d’images RM avec des vertèbres extraites à partir d’images RX pour des ...
  • L'accord de l'adjectif chez les enfants francophones avec un trouble spécifique du langage 

    Adjective concord in Young French-speakers with specific language impairment
    La concordancia adjetival en franco hablantes con trastorno especifico del lenguaje
    Royle, Phaedra; Toupin, Jacinthe; Bourguignon, Nicolas; Trudeau, Natacha; Valois, Daniel (École d'orthophonie et d'audiologie, 2010)
    En dépit du fait que l’étude de la production du syntagme nominal puisse fournir des données riches sur les phénomènes d’accord et de concordance, cette structure demeure peu étudiée. L’étude rapportée ici décrit l’accord intra-nominal, - c’est-à-dire ...
  • L’acquisition du genre quand il est déjà acquis : l’expérience d’enfants hispanophones apprenant le français 

    The acquisition of gender once it has already been mastered: The experience of Spanish-speaking children learning French
    Royle, Phaedra; Bergeron, Eve; Marquis, Alexandra (Orthophonie et Audiologie Canada, 2015)
    This study tests the acquisition of French in Spanish-speaking children by documenting the acquisition of noun phrases in sequential bilingual (Spanish-French) children, compared to native French speakers, matched according to age or language development ...
  • Acquisition of French adjectives in Quebec French as revealed by elicitation data 

    Acquisition of Quebec French adjectives as revealed by elicitation data
    Royle, Phaedra; Valois, Daniel (Cambridge University Press, 2010)
    This study presents data from an elicitation study on French size and color adjectives in noun phrases (DPs), both early acquired structures. Thirty-two francophone children aged 3–5 years participated in the study. Adjectives were elicited using ...
  • Active nuclear import and cytoplasmic retention of activation-induced deaminase 

    Patenaude, Anne-Marie; Orthwein, Alexandre; Hu, Yi; Campo, Vanina A.; Kavli, Bodil; Buschiazzo, Alejandro; Di Noia, Javier M. (2009)
    The enzyme activation-induced deaminase (AID) triggers antibody diversification in B cells by catalyzing deamination and consequently mutation of immunoglobulin genes. To minimize off-target deamination, AID is restrained by several regulatory mechanisms ...
  • Acute insult of ammonia leads to calcium-dependent glutamate release from cultured astrocytes, an effect of pH 

    Rose, Christopher F.; Wolfgang, Kresse; Kettenmann, Helmut (2005)
    Hyperammonemia is a key factor in the pathogenesis of hepatic encephalopathy (HE) as well as other metabolic encephalopathies, such as those associated with inherited disorders of urea cycle enzymes and in Reye's syndrome. Acute HE results in increased ...
  • Addition of exogenous polypeptides on the mammalian reovirus outer capsid using reverse genetics 

    Brochu-Lafontaine, Virginie; Lemay, Guy (Elsevier, 2012-02)
    Addition of exogenous peptide sequences on viral capsids is a powerful approach to study the process of viral infection or to retarget viruses toward defined cell types. Until recently, it was not possible to manipulate the genome of mammalian reovirus ...
  • Adhesion and transcellular migration of neutrophils and B lymphocytes on fibroblasts 

    Couture, Patrick; Paradis-Massie, Jérémie; Oualha, Nadia; Thibault, Gaétan (2009)
    During tissue inflammation, infiltrated leukocytes may have physical contacts with fibroblasts. We observed that neutrophils and B lymphocytes adhered in a larger proportion than T cells on cultured fibroblasts. Microscopy showed that adhesion was also ...
  • Algal Biofuels: Challenges and Opportunities 

    Leite, Gustavo Balduino; Abdelaziz, Ahmed E. M.; Hallenbeck, Patrick C. (Elsevier, 2013)
    Biodiesel production using microalgae is attractive in a number of respects. Here a number of pros and cons to using microalgae for biofuels production are reviewed. Algal cultivation can be carried out using non-arable land and non-potable water with ...
  • Alternative Time Representation in Dopamine Models 

    Rivest, François; Kalaska, John F.; Bengio, Yoshua (Springer Science + Business Media, 2009)
    Données originales publiées dans l'article: Rivest, F, Kalaska, J.F., Bengio, Y. (2009) Alternative time representation in dopamine models. Journal of Computational Neuroscience. doi:10.1007/s10827-009-0191-1
  • Amino acid substitutions in σ1 and μ1 outer capsid proteins are selected during mammalian reovirus adaptation to Vero cells 

    Jabre, Roland; Sandekian, Véronique; Lemay, Guy (Elsevier, 2013-09)
    Establishment of viral persistence in cell culture has previously led to the selection of mammalian reovirus mutants, although very few of those have been characterized in details. In the present study, reovirus was adapted to Vero cells that, in ...
  • Amino acids substitutions in σ1 and μ1 outer capsid proteins of a Vero cell-adapted mammalian orthoreovirus are required for optimal virus binding and disassembly 

    Sandekian, Véronique; Lemay, Guy (Elsevier, 2015-01-01)
    In a recent study, the serotype 3 Dearing strain of mammalian orthoreovirus was adapted to Vero cells; cells that exhibit a limited ability to support the early steps of reovirus uncoating and are unable to produce interferon as an antiviral response ...
  • Ammonia: more than a neurotoxin? 

    Rose, Christopher F. (2014)
  • AnaBench: a Web/CORBA-based workbench for biomolecular sequence analysis 

    Badidi, Elarbi; De Sousa, Cristina; Lang, Franz Bernd; Burger, Gertraud (2003)
    BACKGROUND:Sequence data analyses such as gene identification, structure modeling or phylogenetic tree inference involve a variety of bioinformatics software tools. Due to the heterogeneity of bioinformatics tools in usage and data requirements, ...
  • Analysis of HIV-1 Vpr determinants responsible for cell growth arrest in Saccharomyces cerevisiae 

    Yao, Xiao-Jian; Rougeau, Nicole; Duisit, Ghislaine; Lemay, Julie; Cohen, Éric A. (2004)
    BACKGROUND:The HIV-1 genome encodes a well-conserved accessory gene product, Vpr, that serves multiple functions in the retroviral life cycle, including the enhancement of viral replication in nondividing macrophages, the induction of G2 cell-cycle ...
  • Analysis of scoliosis trunk deformities using ICA 

    Adankon, Mathias M.; Dansereau, Jean; Labelle, Hubert; Cheriet, Farida (2012-07-02)
    This paper describes a method for analyzing scoliosis trunk deformities using Independent Component Analysis (ICA). Our hypothesis is that ICA can capture the scoliosis deformities visible on the trunk. Unlike Principal Component Analysis (PCA), ICA ...
  • Antagonism of tetherin restriction of HIV-1 release by Vpu involves binding and sequestration of the restriction factor in a perinuclear compartment 

    Dubé, Mathieu; Roy, Bibhuti Bhusan; Guiot-Guillain, Pierre; Binette, Julie; Mercier, Johanne; Chiasson, Antoine; Cohen, Éric A. (2010)
    The Vpu accessory protein promotes HIV-1 release by counteracting Tetherin/BST-2, an interferon-regulated restriction factor, which retains virions at the cell-surface. Recent reports proposed beta-TrCP-dependent proteasomal and/or endo-lysosomal ...
  • Anxiety, mood disorders and injection risk behaviors among cocaine users: results from the COSMO study 

    Roy, Élise; Jutras-Aswad, Didier; Bertrand, Karine; Dufour, Magali; Perreault, Michel; Laverdière, Émélie; Bene-Tchaleu, Fabiola; Bruneau, Julie (Wiley, 2015-10)
    Background and Objectives: Despite being common among cocaine users, mental health problems and their relationship with HIV and hepatitis C high risk injection behaviors are poorly documented. This study was undertaken to examine the relationships ...