Now showing items 1-20 of 399

  • A 12-week open-label, multicenter study evaluating the safety and patient-reported efficacy of sodium oxybate in patients with narcolepsy and cataplexy 

    Mamelak, Mortimer; Swick, Todd; Emsellem, Helene; Montplaisir, Jacques-Yves; Lai, Chinglin; Black, Jed (Elsevier, 2015)
    Objective: This study aimed to evaluate safety and efficacy of sodium oxybate (SXB) titrated to effect. Methods: SXB-naive patients who had participated in a randomized SXB clinical trial and had not been titrated to adequate clinical effect were ...
  • 2021 ISHEN guidelines on animal models of hepatic encephalopathy 

    DeMorrow, Sharon; Cudalbu, Cristina; Davies, Nathan A.; Jayakumar, Arumugam R.; Rose, Christopher (Wiley, 2021-04-01)
    This working group of the International Society of Hepatic Encephalopathy and Nitrogen Metabolism (ISHEN) was commissioned to summarize and update current efforts in the development and characterization of animal models of hepatic encephalopathy (HE). ...
  • The 20S proteasome core, active within apoptotic exosome-like vesicles, induces autoantibody production and accelerates rejection 

    Dieudé, Mélanie; Bell, Christina; Turgeon, Julie; Beillevaire, Déborah; Yang, Bing; Hamelin, Katia; Qi, Shijie; Pallet, Nicolas; Béland, Chanel; Dhahri, Wahiba; Cailhier, Jean-François; Rousseau, Matthieu; Duchez, Anne-Claire; Lévesque, Tania; Lau, Arthur; Rondeau, Christiane; Gingras, Diane; Muruve, Danie; Rivard, Alain; Cardinal, Héloïse; Perreault, Claude; Desjardins, Michel; Boilard, Éric; Thibault, Pierre; Hébert, Marie-Josée (American Association for the Advancement of Science, 2015-12-16)
    Autoantibodies to components of apoptotic cells, such as anti-perlecan antibodies, contribute to rejection in organ transplant recipients. However, mechanisms of immunization to apoptotic components remain largely uncharacterized. We used large-scale ...
  • 3D Cohort Study : The Integrated Research Network in Perinatology of Quebec and Eastern Ontario 

    Fraser, William; Shapiro, Gabriel; Dubois, Lise; Pasquier, Jean-Charles; Julien, Pierre; Bérard, Anick; Muckle, Gina; Trasler, Jacquetta; Tremblay, Richard Ernest; Abenhaim, Haim; Welt, Michel; Bissonnette, François; Bédard, Marie-Josée; Bujold, Emmanuel; Gagnon, Robert; Michaud, Jacques; Girard, Isabelle; Moutquin, Jean-Marie; Marc, Isabelle; Monnier, Patricia; Luo, Zhong-Cheng; 3D Study Group; Séguin, Jean; Audibert, François (Wiley, 2016)
    Background: The 3D Cohort Study (Design, Develop, Discover) was established to help bridge knowledge gaps about the links between various adverse exposures during pregnancy with birth outcomes and later health outcomes in children. Methods: Pregnant ...
  • 3D registration of MR and X-ray spine images using an articulated model 

    Harmouche, Rola; Cheriet, Farida; Labelle, Hubert; Dansereau, Jean (2012-07)
    Présentation: Cet article a été publié dans le journal : Computerised medical imaging and graphics (CMIG). Le but de cet article est de recaler les vertèbres extraites à partir d’images RM avec des vertèbres extraites à partir d’images RX pour des ...
  • The 3D-Transition study : objectives, methods, and implementation of an innovative planned missing data design 

    Rioux, Charlie; Parent, Sophie; Castellanos Ryan, Natalie; Archambault, Isabelle; Boivin, Michel; Herba, Catherine; Lupien, Sonia; Marc, Isabelle; Muckle, Gina; Fraser, William; Séguin, Jean (Oxford University Press, 2021-05-12)
    The prevalence of mental health problems represents a significant burden on school and community health resources as early as preschool. Reducing this burden requires a better understanding of the developmental mechanisms linking children’s early ...
  • L'accord de l'adjectif chez les enfants francophones avec un trouble spécifique du langage 

    Adjective concord in Young French-speakers with specific language impairment
    La concordancia adjetival en franco hablantes con trastorno especifico del lenguaje
    Royle, Phaedra; Toupin, Jacinthe; Bourguignon, Nicolas; Trudeau, Natacha; Valois, Daniel (École d'orthophonie et d'audiologie, 2010)
    En dépit du fait que l’étude de la production du syntagme nominal puisse fournir des données riches sur les phénomènes d’accord et de concordance, cette structure demeure peu étudiée. L’étude rapportée ici décrit l’accord intra-nominal, - c’est-à-dire ...
  • L’acquisition du genre quand il est déjà acquis : l’expérience d’enfants hispanophones apprenant le français 

    The acquisition of gender once it has already been mastered: The experience of Spanish-speaking children learning French
    Royle, Phaedra; Bergeron, Eve; Marquis, Alexandra (Orthophonie et Audiologie Canada, 2015)
    This study tests the acquisition of French in Spanish-speaking children by documenting the acquisition of noun phrases in sequential bilingual (Spanish-French) children, compared to native French speakers, matched according to age or language development ...
  • Acquisition of French adjectives in Quebec French as revealed by elicitation data 

    Acquisition of Quebec French adjectives as revealed by elicitation data
    Royle, Phaedra; Valois, Daniel (Cambridge University Press, 2010)
    This study presents data from an elicitation study on French size and color adjectives in noun phrases (DPs), both early acquired structures. Thirty-two francophone children aged 3–5 years participated in the study. Adjectives were elicited using ...
  • Active nuclear import and cytoplasmic retention of activation-induced deaminase 

    Patenaude, Anne-Marie; Orthwein, Alexandre; Hu, Yi; Campo, Vanina A.; Kavli, Bodil; Buschiazzo, Alejandro; Di Noia, Javier M. (2009)
    The enzyme activation-induced deaminase (AID) triggers antibody diversification in B cells by catalyzing deamination and consequently mutation of immunoglobulin genes. To minimize off-target deamination, AID is restrained by several regulatory mechanisms ...
  • Activity monitor placed at the non-paretic ankle is accurate in measuring step counts during community walking in post-stroke individuals : a validation study 

    Duclos, Noémie C.; Aguiar, Larissa Tavares; Faria, Christina Danielli Coelho de Morais; Nadeau, Sylvie; Duclos, Cyril (Wiley, 2019-01-28)
    Background: Different environmental factors may affect the accuracy of step-count activity monitors (AM). However, the validationconditions for AM accuracy largely differ from ecological environments.Objectives: To assess and compare the accuracy of ...
  • Acute carotid stenting in patients undergoing thrombectomy : a systematic review and meta-analysis 

    Dufort, Gabrielle; Chen, Bing Yu; Jacquin, Grégory; Keezer, Mark; Labrie, Marilyn; Rioux, Bastien; Stapf, Christian; Ziegler, Daniela; Y Poppe, Alexandre (BMJ Publishing Group, 2020-06-12)
    Background The benefit of acute carotid stenting compared with no acute stenting on clinical outcomes among patients with tandem lesions (TL) undergoing endovascular thrombectomy (EVT) remains unknown. Methods We conducted a a systematic review and ...
  • Acute insult of ammonia leads to calcium-dependent glutamate release from cultured astrocytes, an effect of pH 

    Rose, Christopher; Wolfgang, Kresse; Kettenmann, Helmut (2005)
    Hyperammonemia is a key factor in the pathogenesis of hepatic encephalopathy (HE) as well as other metabolic encephalopathies, such as those associated with inherited disorders of urea cycle enzymes and in Reye's syndrome. Acute HE results in increased ...
  • Addition of exogenous polypeptides on the mammalian reovirus outer capsid using reverse genetics 

    Brochu-Lafontaine, Virginie; Lemay, Guy (Elsevier, 2012-02)
    Addition of exogenous peptide sequences on viral capsids is a powerful approach to study the process of viral infection or to retarget viruses toward defined cell types. Until recently, it was not possible to manipulate the genome of mammalian reovirus ...
  • Adhesion and transcellular migration of neutrophils and B lymphocytes on fibroblasts 

    Couture, Patrick; Paradis-Massie, Jérémie; Oualha, Nadia; Thibault, Gaétan (2009)
    During tissue inflammation, infiltrated leukocytes may have physical contacts with fibroblasts. We observed that neutrophils and B lymphocytes adhered in a larger proportion than T cells on cultured fibroblasts. Microscopy showed that adhesion was also ...
  • Albumin dialysis : a new therapeutic strategy for intoxication from protein-bound drugs 

    Sen, Sambit; Ytrebø, Lars M.; Rose, Christopher; Fuskevaag, Ole-Martin; Davies, Nathan A.; Nedredal, Geir I.; Williams, Roger; Revhaug, Arthur; Jalan, Rajiv (Springer, 2004-01-21)
    Abstract Objective: Although water-soluble drugs can be removed by haemofiltration/haemodialysis, morbidity and mortality from intoxication with protein-bound drugs remains high. The present study investigates whether albumin dialysis in the form of ...
  • Algal Biofuels: Challenges and Opportunities 

    Leite, Gustavo Balduino; Abdelaziz, Ahmed E. M.; Hallenbeck, Patrick C. (Elsevier, 2013)
    Biodiesel production using microalgae is attractive in a number of respects. Here a number of pros and cons to using microalgae for biofuels production are reviewed. Algal cultivation can be carried out using non-arable land and non-potable water with ...
  • Altered sensory-weighting mechanisms is observed in adolescents with idiopathic scoliosis 

    Simoneau, Martin; Mercier, Pierre; Blouin, Jean; Allard, Paul; Teasdale, Normand (2006)
    BACKGROUND:Scoliosis is the most common type of spinal deformity. In North American children, adolescent idiopathic scoliosis (AIS) makes up about 90% of all cases of scoliosis. While its prevalence is about 2% to 3% in children aged between 10 to 16 ...
  • Alternative Time Representation in Dopamine Models 

    Rivest, François; Kalaska, John F.; Bengio, Yoshua (Springer Science + Business Media, 2009)
    Données originales publiées dans l'article: Rivest, F, Kalaska, J.F., Bengio, Y. (2009) Alternative time representation in dopamine models. Journal of Computational Neuroscience. doi:10.1007/s10827-009-0191-1
  • Amino acid substitutions in σ1 and μ1 outer capsid proteins are selected during mammalian reovirus adaptation to Vero cells 

    Jabre, Roland; Sandekian, Véronique; Lemay, Guy (Elsevier, 2013-09)
    Establishment of viral persistence in cell culture has previously led to the selection of mammalian reovirus mutants, although very few of those have been characterized in details. In the present study, reovirus was adapted to Vero cells that, in ...