Now showing items 1-20 of 133

  • Interleukin-8 predicts fatigue at 12 months post-injury in children with traumatic brain injury 

    Interleukin‐8 predict fatigue in child TBI
    Crichton, Alison; Ignjatovic, Vera; Babl, Franz E.; Oakley, Ed; Greenham, Mardee; Hearps, Stephen; Delzoppo, Carmel; Beauchamp, Miriam; Guerguerian, Anne‐Marie; Boutis, Kathy; Hubara, Evyatar (Mary Ann Liebert, 2019-12-27)
    Despite many children experiencing fatigue after childhood brain injury, little is known about the predictors of this complaint. To date, traditional indices of traumatic brain injury (TBI) severity have not reliably predicted persisting fatigue ...
  • A phase 2 study of trametinib for patients with pediatric glioma or plexiform neurofibroma with refractory tumor and activation of the MAPK/ERK pathway 

    Perreault, Sébastien; Larouche, Valérie; Tabor, Uri; Hawkin, Cynthia; Lippé, Sarah; Ellezam, Benjamin; Décarie, Jean-Claude; Théoret, Yves; Métras, Marie-Élaine; Sultan, Serge; Cantin, Édith; Routhier, Marie-Ève; Caru, Maxime; Legault, Geneviève; Bouffet, Éric; Lafay-Cousin, Lucie; Hukin, Juliette; Erker, Craig; Jabado, Nada (BMC, 2019-12-27)
    Background Pediatric low-grade gliomas (PLGG) are the most frequent brain tumors in children. Up to 50% will be refractory to conventional chemotherapy. It is now known that the majority of PLGG have activation of the MAPK/ERK pathway. The same pathway ...
  • Pathways to recovery among homeless people with mental illness: Is impulsiveness getting in the way? 

    Leclair, Marichelle C.; Lemieux, Ashley J.; Roy, Laurence; Martin, Michael S.; Latimer, Éric; Crocker, Anne (SAGE, 2019-11-25)
    Objective: This study investigates the association between impulsiveness and six dimensions of recovery among homeless people with mental illness. Method: The sample was composed of 418 participants of a randomized controlled trial of Housing ...
  • Prolonged and unprolonged complex febrile seizures differently affect frontal theta brain activity 

    Thébault-Dagher, Fanny; Deguire, Florence; Knoth, Inga Sophia; Lafontaine, Marc Philippe; Barlaam, Fanny; Côté, Valérie; Agbogba, Kristian; Lippé, Sarah (Elsevier, 2019-11-07)
    Objective: Studies have identified persistent cognitive and functional deficits, which could be linked to each other, in children with complex febrile seizures (FS). Our aim was to investigate differences in brain activity in children with a history ...
  • Education as a moderator of the relationship between episodic memory and amyloid load in normal aging 

    Joannette, Maude; Bocti, Christian; Sévigny Dupont, Pénélope; Lavallée, Marie Maxime; Nikelski, Jim; Vallet, Guillaume; Chertkow, Howard; Joubert, Sven (Oxford University Press, 2019-10-23)
    The current study explored whether education, a proxy of cognitive reserve, modifies the association between episodic memory (EM) performance and βeta-amyloid load (Aβ), a biomarker of Alzheimer’s disease, in a cohort of cognitively normal older ...
  • Sleep-wake disturbances in hospitalized patients with traumatic brain injury: association with brain trauma but not with an abnormal melatonin circadian rhythm 

    Duclos, Catherine; Dumont, Marie; Paquet, Jean; Blais, Hélène; Van der Maren, Solenne; Menon, David K.; Bernard, Francis; Gosselin, Nadia (Oxford University Press, 2019-09-28)
    Study Objectives: To test whether the sleep-wake cycle disruption in patients hospitalized with traumatic brain injury (TBI) 1) is also found in patients with traumatic injuries other than TBI (nonTBI); and 2) is associated to a weaker or abnormal ...
  • Amyloid burden and white matter hyperintensities mediate age-related cognitive differences 

    Sévigny Dupont, Pénélope; Bocti, Christian; Joannette, Maude; Lavallée, Marie Maxime; Nikelski, Jim; Vallet, Guillaume; Chertkow, Howard; Joubert, Sven (Elsevier, 2019-08)
    This study examined the additive versus synergistic contribution of beta-amyloid (Aβ) and white matter hyperintensities (WMHs) across 7 cognitive domains in 104 cognitively normal older adults. It also measured the extent to which age-related differences ...
  • Subcortical amyloid relates to cortical morphology in cognitively normal individuals 

    Rahayel, Shady; Bocti, Christian; Sévigny Dupont, Pénélope; Joannette, Maude; Lavallée, Marie Maxime; Nikelski, Jim; Chertkow, Howard; Joubert, Sven (Springer, 2019-07-25)
    Purpose Amyloid (Aβ) brain deposition can occur in cognitively normal individuals and is associated with cortical volume abnormalities. Aβ-related volume changes are inconsistent across studies. Since volume is composed of surface area and thickness, ...
  • A MEG study of the neural substrates of semantic processing in semantic variant primary progressive aphasia 

    Pineault, Jessica; Jolicoeur, Pierre; Grimault, Stephan; Lacombe, Jacinthe; Brambati, Simona Maria; Bier, Nathalie; Chayer, Céline; Joubert, Sven (Taylor & Francis, 2019-07-01)
    Despite a well-documented pattern of semantic memory (SM) impairment, the patterns of brain activation during semantic processing in svPPA still remain poorly understood. The current study aimed to investigate the neural substrates of residual semantic ...
  • Disentangling the direction of associations between sleep and temperament in toddlers 

    Bastien, Laurianne; Tétreault, Émilie; Bernier, Annie (Taylor & Francis, 2019-06-24)
    Objectives/Background: Although much research has investigated the associations between children’s sleep and their temperament, the direction of these associations remains unclear, largely due to a lack of longitudinal studies with repeated assessments ...
  • Subcortical amyloid load is associated with shape and volume in cognitively normal individuals 

    Subcortical Aβ associates to morphometry
    Rahayel, Shady; Bocti, Christian; Sévigny Dupont, Pénélope; Joannette, Maude; Lavallée, Marie Maxime; Nikelski, Jim; Chertkow, Howard; Joubert, Sven (Wiley, 2019-05-21)
    Amyloid-beta (Aβ) deposition is one of the main hallmarks of Alzheimer’s disease. The study assessed the associations between cortical and subcortical 11C-Pittsburgh Compound B retention, namely in the hippocampus, amygdala, putamen, caudate, pallidum, ...
  • Aging and language : maintenance of morphological representations in older adults 

    Royle, Phaedra; Steinhauer, Karsten; Dessureault, Émie; Herbay, Alexandre C.; Brambati, Simona Maria (Frontiers media, 2019-05-15)
    Studies employing primed lexical decision tasks have revealed morphological facilitation effects in children and young adults. It is unknown if this effect is preserved or diminished in older adults. In fact, only few studies have investigated ...
  • Febrile seizures and increased stress sensitivity in children : how it relates to seizure characteristics 

    Thébault-Dagher, Fanny; Lafontaine, Marc Philippe; Knoth, Inga Sophia; Deguire, Florence; Sheppard, Emilie; Cook, Ramona; Lagacé, Maryse; Gravel, Jocelyn; Lupien, Sonia; Lippé, Sarah (Elsevier, 2019-05)
    BACKGROUND: Studies suggest that the relationship between seizures and stress starts early in life. However, evidence of long-term altered stress reactivity following early-life seizures is lacking. Our objectives were to assess alterations in stress ...
  • Visual and auditory perceptual strength norms for 3,596 French nouns and their relationship with other psycholinguistic variables 

    Chedid, Georges; Brambati, Simona Maria; Bedetti, Christophe; Rey, Amandine E.; Wilson, Maximiliano A.; Vallet, Guillaume (Springer, 2019-04-23)
    Perceptual experience plays a critical role in the conceptual representation of words. Higher levels of semantic variables such as imageability, concreteness, and sensory experience are generally associated with faster and more accurate word processing. ...
  • Towards an integrated understanding of aggression in the general population : findings from an epidemiological catchment area study 

    Aggression in the general population
    Leclair, Marichelle C.; Roy, Laurence; Caron, Jean; Crocker, Anne; Reyes, Andrea (Elsevier, 2019-03-23)
    The goal of this study is to identify patterns of various forms of aggression in the general population and their psychosocial and environmental correlates. Data from the Montreal Epidemiological Catchment Area study (N = 1855) were analyzed using ...
  • Brain white matter damage and its association with neuronal synchrony during sleep 

    Sanchez, Erlan; El-Khatib, Héjar; Arbour, Caroline; Bedetti, Christophe; Blais, Hélène; Marcotte, Karine; Baril, Andrée-Ann; Descoteaux, Maxime; Gilbert, Danielle; Carrier, Julie; Gosselin, Nadia (Oxford University Press, 2019-01-28)
    The restorative function of sleep partly relies on its ability to deeply synchronize cerebral networks to create large slow oscillations observable with EEG. However, whether a brain can properly synchronize and produce a restorative sleep when it ...
  • Obstructive sleep apnea and the risk of cognitive decline in older adults 

    Gosselin, Nadia; Baril, Andrée-Ann; Osorio, Ricardo S.; Kaminska, Marta; Carrier, Julie (American Thoracic Society, 2019-01-15)
    Obstructive sleep apnea causes intermittent hypoxia and sleep fragmentation and affects at least 20% of individuals after the age of 65. There is accumulating evidence that obstructive sleep apnea may impact brain structure and function. Recent cohort ...
  • Test-retest reliability of diffusion measures extracted along white matter language fiber bundles using HARDI-based tractography 

    Boukadi, Mariem; Marcotte, Karine; Bedetti, Christophe; Houde, Jean-Christophe; Desautels, Alex; Deslauriers-Gauthier, Samuel; Chapleau, Marianne; Boré, Arnaud; Descoteaux, Maxime; Brambati, Simona Maria (Frontiers media, 2019-01-14)
    High angular resolution diffusion imaging (HARDI)-based tractography has been increasingly used in longitudinal studies on white matter macro- and micro-structural changes in the language network during language acquisition and in language impairments. ...
  • A longitudinal investigation of sleep and daytime wakefulness in children and youth with concussion 

    Wiseman-Hakes, Catherine; Gosselin, Nadia; Sharma, Bhanu; Langer, Laura; Gagnon, Isabelle (SAGE, 2019-01-10)
    A high proportion of adults who sustain a concussion identify changes in their sleep during the acute stage, typically reporting an increased need for sleep or nonrestful sleep. Our understanding of sleep following concussion is less well understood ...
  • The impact of Housing First on criminal justice outcomes among homeless people with mental illness : a systematic review. 

    Leclair, Marichelle C.; Deveaux, Félicia; Roy, Laurence; Goulet, Marie-Hélène; Latimer, Éric; Crocker, Anne (SAGE, 2019-01-06)
    Objective: Housing First is increasingly put forward as an important component of a pragmatic plan to end homelessness. The literature evaluating the impact of Housing First on criminal justice involvement has not yet been systematically examined. The ...