• Are age and sex effects on sleep slow waves only a matter of EEG amplitude ? 

    Rosinvil, Thaïna; Bouvier, Justin; Dubé, Jonathan; Lafrenière, Alexandre; Bouchard, Maude; Cyr-Cronier, Jessica; Nadia, Gosselin; Carrier, Julie; Lina, Jean-Marc (Oxford University Press, 2020-09-15)
    Aging is associated with reduced slow wave (SW) density (number SW/min in nonrapid-eye movement sleep) and amplitude. It has been proposed that an age-related decrease in SW density may be due to a reduction in electroencephalogram (EEG) amplitude ...
  • Biomarkers of dementia in obstructive sleep apnea 

    Baril, Andrée-Ann; Carrier, Julie; Lafrenière, Alexandre; Warby, Simon; Poirier, Judes; Osorio, Ricardo S.; Ayas, Najib; Dubé, Marie-Pierre; Petit, Dominique; Gosselin, Nadia; Canadian Sleep and Circadian Network (Elsevier, 2018-08-13)
    Epidemiologic and mechanistic evidence is increasingly supporting the notion that obstructive sleep apnea is a risk factor for dementia. Hence, the identification of patients at risk of cognitive decline due to obstructive sleep apnea may significantly ...
  • REM sleep is associated with the volume of the cholinergic basal forebrain in aMCI individuals 

    André, Claire; Martineau‑Dussault, Marie‑Ève; Daneault, Véronique; Blais, Hélène; Frenette, Sonia; Lorrain, Dominique; Hudon, Carol; Bastien, Célyne; Petit, Dominique; Lafrenière, Alexandre; Thompson, Cynthia; Montplaisir, Jacques-Yves; Gosselin, Nadia; Carrier, Julie (BMC, 2023-09-08)
    Background Rapid-eye movement (REM) sleep highly depends on the activity of cholinergic basal forebrain (BF) neurons and is reduced in Alzheimer’s disease. Here, we investigated the associations between the volume of BF nuclei and REM sleep ...
  • Sleep slow waves’ negative-to-positive-phase transition : a marker of cognitive and apneic status in aging 

    Lafrenière, Alexandre; Lina, Jean-Marc; Hernandez, Jimmy; Bouchard, Maude; Gosselin, Nadia; Carrier, Julie (Oxford University Press, 2022-10-11)
    The sleep slow-wave (SW) transition between negative and positive phases is thought to mirror synaptic strength and likely depends on brain health. This transition shows signifcant age-related changes but has not been investigated in pathological ...