• Are NREM sleep characteristics associated to subjective sleep complaints after mild traumatic brain injury? 

    Sleep after mild TBI
    Arbour, Caroline; Khoury, Samar; Lavigne, Gilles; Gagnon, Katia; Gaétan, Poirier; Montplaisir, Jacques-Yves; Carrier, Julie; Gosselin, Nadia (Elsevier, 2015-04)
    Sleep complaints are common after mild traumatic brain injury (mTBI). While recent find-ings suggest that sleep macro-architecture is preserved in mTBI, features of non-rapid eye movement(NREM) sleep micro-architecture including electroencephalography ...
  • Association between waking electroencephalography and cognitive event-related potentials in patients with obstructive sleep apnea 

    EEG and ERP in OSA
    Baril, Andrée-Ann; Gagnon, Katia; Gagnon, Jean-François; Montplaisir, Jacques-Yves; Gosselin, Nadia (Elsevier, 2013)
    Objective: Abnormal event-related potentials (ERP) and slowing of the waking electroencephalographic (EEG) activity have been reported in patients with obstructive sleep apneas (OSA). This study aimed at evaluating whether an association exists between ...
  • Biomarkers of dementia in obstructive sleep apnea 

    Baril, Andrée-Ann; Carrier, Julie; Lafrenière, Alexandre; Warby, Simon; Poirier, Judes; Osorio, Ricardo S.; Ayas, Najib; Dubé, Marie-Pierre; Petit, Dominique; Gosselin, Nadia; Canadian Sleep and Circadian Network (Elsevier, 2018-08-13)
    Epidemiologic and mechanistic evidence is increasingly supporting the notion that obstructive sleep apnea is a risk factor for dementia. Hence, the identification of patients at risk of cognitive decline due to obstructive sleep apnea may significantly ...
  • Brain white matter damage and its association with neuronal synchrony during sleep 

    Sanchez, Erlan; El-Khatib, Héjar; Arbour, Caroline; Bedetti, Christophe; Blais, Hélène; Marcotte, Karine; Baril, Andrée-Ann; Descoteaux, Maxime; Gilbert, Danielle; Carrier, Julie; Gosselin, Nadia (Oxford University Press, 2019-01-28)
    The restorative function of sleep partly relies on its ability to deeply synchronize cerebral networks to create large slow oscillations observable with EEG. However, whether a brain can properly synchronize and produce a restorative sleep when it ...
  • Cerebral white matter diffusion properties and free‐water with obstructive sleep apnea severity in older adults 

    Baril, Andrée‐Ann; Gagnon, Katia; Descoteaux, Maxime; Bedetti, Christophe; Chami, Sirin; Sanchez, Erlan; Montplaisir, Jacques-Yves; De Beaumont, Louis; Gilbert, Danielle; Poirier, Judes; Pelleieux, Sandra; Osorio, Ricardo S.; Carrier, Julie; Gosselin, Nadia (Wiley, 2020-03-13)
    Characterizing the effects of obstructive sleep apnea (OSA) on the aging brain could be key in our understanding of neurodegeneration in this population. Our objective was to assess white matter properties in newly diagnosed and untreated adults with ...
  • Changes in regional cerebral perfusion over time in idiopathic REM sleep behavior disorder 

    Baril, Andrée‐Ann; Gagnon, Jean-François; Pelletier, Amélie; Soucy, Jean-Paul; Gosselin, Nadia; Postuma, Ronald B.; Montplaisir, Jacques-Yves (Wiley, 2020-05-27)
    Background Idiopathic rapid eye movement sleep behavior disorder is associated with increased risk of neurodegeneration, but the temporal evolution of regional perfusion, a marker of cerebral activity, has not been characterized. The objective of the ...
  • The clinical utility of repetitive transcranial magnetic stimulation in reducing the risks of transitioning from acute to chronic pain in traumatically injured patients 

    Jodoin, Marianne; Rouleau, Dominique; Larson-Dupuis, Camille; Gosselin, Nadia; De Beaumont, Louis (Elsevier, 2017-07-08)
    Pain is a multifaceted condition and a major ongoing challenge for healthcare professionals having to treat patients in whom pain put them at risk of developing other conditions. Significant efforts have been invested in both clinical and research ...
  • Does age matter? A mixed methods study examining determinants of good recovery and resilience in young and middle-aged adults following moderate-to-severe traumatic brain injury 

    Recovery and resilience after TBI
    Arbour, Caroline; Gosselin, Nadia; Levert, Marie‐Josée; Gauvin-Lepage, Jérôme; Michallet, Bernard; Lefebvre, Hélène (Wiley, 2017-07-05)
    Aim: To examine whether age contributes to functional recovery and resilience after moderate-to-severe traumatic brain injury (TBI). Background: The ability to recover from TBI may change across the lifespan, but the influence of age on TBI outcome ...
  • EEG connectivity across sleep cycles and age 

    Bouchard, Maude; Lina, Jean-Marc; Gaudreault, Pierre-Olivier; Dubé, Jonathan; Gosselin, Nadia; Carrier, Julie (American academy of sleep medicine, 2019-11-06)
    Study Objectives In young adults, sleep is associated with important changes in cerebral connectivity during the first cycle of non-rapid eye movement (NREM) sleep. Our study aimed to evaluate how electroencephalography (EEG) connectivity during sleep ...
  • Effects of menopause on sleep quality and sleep disorders : Canadian longitudinal study on aging 

    Zolfaghari, Sheida; Yao, Chun; Thompson, Cynthia; Gosselin, Nadia; Desautels, Alex; Dang-Vu, Thien Thanh; Postuma, Ronald B.; Carrier, Julie (Lippincott, Williams & Wilkins, 2020-02-29)
    OBJECTIVES:Sleep complaints are common during the menopause transition. However, it is difficult to disentangle changes in sleep related to aging from those directly due to menopause. We compared sleep disorders in 45 to 60-year-old women in a large ...
  • Evolution of severe sleep-wake cycle disturbances following traumatic brain injury: a case study in both acute and subacute phases post-injury 

    Duclos, Catherine; Dumont, Marie; Potvin, Marie-Julie; Desautels, Alex; Gilbert, Danielle; Menon, David K.; Bernard, Francis; Gosselin, Nadia (BMC, 2016)
    Background. Sleep-wake disturbances are frequently reported following traumatic brain injury (TBI), but they remain poorly documented in the acute stage of injury. Little is known about their origin and evolution. Case presentation. This study presents ...
  • Gray matter hypertrophy and thickening with obstructive sleep apnea in middle-aged and older adults 

    Gray matter increases with obstructive sleep apnea
    Baril, Andrée-Ann; Gagnon, Katia; Brayet, Pauline; Montplaisir, Jacques-Yves; De Beaumont, Louis; Carrier, Julie; Lafond, Chantal; L’Heureux, Francis; Gagnon, Jean-François; Gosselin, Nadia (American Thoracic Society, 2017-06-01)
    Rationale: Obstructive sleep apnea causes intermittent hypoxemia, hemodynamic fluctuations, and sleep fragmentation, all of which could damage cerebral gray matter that can be indirectly assessed with neuroimaging. Objectives: To investigate whether ...
  • The impact of poor sleep on cognition and activities of daily living after traumatic brain injury : a review 

    Sleep and everyday activities after TBI
    Duclos, Catherine; Beauregard, Marie-Pascale; Bottari, Carolina; Ouellet, Marie-Christine; Gosselin, Nadia (Wiley, 2014)
    Background/aim : Patients frequently report sleep disrup-tions or insomnia during their hospital stay, particularlyafter a traumatic brain injury (TBI). The consequences ofthese sleep disturbances on everyday activities are not welldocumented and are ...
  • Investigating the incidence and magnitude of heterotopic ossification with and without joints involvement in patients with a limb fracture and mild traumatic brain injury 

    Jodoin, Marianne; Rouleau, Dominique; Therrien, Erik; Chauny, Jean-Marc; Sandman, Emilie; Larson-Dupuis, Camille; Leduc, Stéphane; Gosselin, Nadia; De Beaumont, Louis (Elsevier, 2019-08-13)
    Objectives: This study seeks to evaluate the incidence rate of heterotopic ossification (HO) formation in patients afflicted by an isolated limb fracture (ILF) and a concomitant mild traumatic brain injury (mTBI). Methods: The current study is an ...
  • A longitudinal investigation of sleep and daytime wakefulness in children and youth with concussion 

    Wiseman-Hakes, Catherine; Gosselin, Nadia; Sharma, Bhanu; Langer, Laura; Gagnon, Isabelle (SAGE, 2019-01-10)
    A high proportion of adults who sustain a concussion identify changes in their sleep during the acute stage, typically reporting an increased need for sleep or nonrestful sleep. Our understanding of sleep following concussion is less well understood ...
  • Moderate to severe acute pain disturbs motor cortex intracortical inhibition and facilitation in orthopedic trauma patients : a TMS study 

    Jodoin, Marianne; Rouleau, Dominique; Bellemare, Audrey; Provost, Catherine; Larson-Dupuis, Camille; Sandman, Emilie; Laflamme, Georges-Yves; Benoit, Benoit; Leduc, Stéphane; Levesque, Martine; Gosselin, Nadia; De Beaumont, Louis (Public library of science, 2020-03-20)
    Objective Primary motor (M1) cortical excitability alterations are involved in the development and maintenance of chronic pain. Less is known about M1-cortical excitability implications in the acute phase of an orthopedic trauma. This study aims to ...
  • Obstructive sleep apnea and the risk of cognitive decline in older adults 

    Gosselin, Nadia; Baril, Andrée-Ann; Osorio, Ricardo S.; Kaminska, Marta; Carrier, Julie (American Thoracic Society, 2019-01-15)
    Obstructive sleep apnea causes intermittent hypoxia and sleep fragmentation and affects at least 20% of individuals after the age of 65. There is accumulating evidence that obstructive sleep apnea may impact brain structure and function. Recent cohort ...
  • Obstructive sleep apnea during REM sleep and daytime cerebral functioning : a regional cerebral blood flow study using high-resolution SPECT 

    Baril, Andrée-Ann; Gagnon, Katia; Brayet, Pauline; Montplaisir, Jacques-Yves; Carrier, Julie; Soucy, Jean-Paul; Lafond, Chantal; Blais, Hélène; d’Aragon, Caroline; Gagnon, Jean-François; Gosselin, Nadia (SAGE, 2018-11-22)
    Obstructive sleep apnea (OSA) predominantly during rapid eye movement (REM) sleep may have impacts on brain health, even in milder OSA cases. Here, we evaluated whether REM sleep OSA is associated with abnormal daytime cerebral functioning using ...
  • Parallel recovery of consciousness and sleep in acute traumatic brain injury 

    Duclos, Catherine; Dumont, Marie; Arbour, Caroline; Paquet, Jean; Blais, Hélène; Menon, David K.; De Beaumont, Louis; Bernard, Francis; Gosselin, Nadia (American Academy of Neurology, 2017)
    Objective: To investigate whether the progressive recuperation of consciousness was associated with the reconsolidation of sleep and wake states in hospitalized patients with acute traumatic brain injury (TBI). Methods: This study comprised 30 ...
  • Regional cerebral blood flow during wakeful rest in older subjects with mild to severe obstructive sleep apnea 

    Cerebral perfusion in OSA
    Baril, Andrée-Ann; Gagnon, Katia; Arbour, Caroline; Soucy, Jean-Paul; Montplaisir, Jacques-Yves; Gagnon, Jean-François; Gosselin, Nadia (Oxford University Press, 2015)
    Objectives: To evaluate changes in regional cerebral blood flow (rCBF) during wakeful rest in older subjects with mild to severe obstructive sleep apnea (OSA) and healthy controls, and to identify markers of OSA severity that predict altered ...