Browsing Faculté des arts et des sciences – Département de psychologie - Travaux et publications by Subject "Alzheimer’s disease"
Now showing items 1-14 of 14
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Atrophy in Alzheimer’s disease and semantic dementia : an ALE meta-analysis of voxel-based morphometry studies
(IOS Press, 2016)Background/Objectives: Alzheimer’s disease (AD) and semantic dementia (SD) have distinct episodic memory profiles despite the hippocampal atrophy that characterizes both diseases. The aim of this study was to delineate the pattern of gray matter (GM) ... -
Biomarkers of dementia in obstructive sleep apnea
(Elsevier, 2018-08-13)Epidemiologic and mechanistic evidence is increasingly supporting the notion that obstructive sleep apnea is a risk factor for dementia. Hence, the identification of patients at risk of cognitive decline due to obstructive sleep apnea may significantly ... -
Connected speech features from picture description in Alzheimer's disease: a systematic review
(IOS Press, 2018-08-21)The language changes that occur over the course of Alzheimer’s disease (AD) can impact communication abilities and have profound functional consequences. Picture description tasks can be used to approximate everyday communication abilities of AD patients. ... -
Connected speech markers of amyloid burden in primary progressive aphasia
(Elsevier, 2021-10-07)INTRODUCTION Positron emission tomography (PET) amyloid imaging has become an important part of the diagnostic workup for patients with primary progressive aphasia (PPA) and uncertain underlying pathology. Here, we employ a semi-automated analysis of ... -
Deformation-based shape analysis of the hippocampus in the semantic variant of primary progressive aphasia and Alzheimer’s disease
(Elsevier, 2020-06-03)Background Increasing evidence shows that the semantic variant of primary progressive aphasia (svPPA) is characterized by hippocampal atrophy. However, less is known about disease-related morphological hippocampal changes. The goal of the present study ... -
Evidence of a relation between hippocampal volume, white matter hyperintensities, and cognition in subjective cognitive decline and mild cognitive impairment
(Oxford University Press, 2019-10-26)Objective: The concepts of mild cognitive impairment (MCI) and subjective cognitive decline (SCD) have been proposed to identify individuals in the early stages of Alzheimer’s disease (AD), or other neurodegenerative diseases. One approach to validate ... -
An examination of semantic impairment in amnestic MCI and AD : What can we learn from verbal fluency?
(Oxford University Press, 2019-04-17)Introduction The Verbal Fluency Test (VF) is commonly used in neuropsychology. Some studies have demonstrated a marked impairment of semantic VF compared to phonemic VF in Alzheimer’s disease (AD). Since amnestic Mild Cognitive Impairment (aMCI) is ... -
An examination of semantic performance in mild cognitive impairment progressors and nonprogressors
(American psychological association, 2024-02-15)Background. Mild Cognitive Impairment (MCI) is a risk factor for developing Alzheimer’s disease (AD), and about half of older people with MCI will progress to AD within the next five years. The aim of the present study was to compare the semantic ... -
The impact of time and repeated exposure on famous person knowledge in amnestic Mild cognitive impairment and Alzheimer’s disease
(2017)Objective: Famous people knowledge has been shown to be impaired early in Alzheimer’s disease (AD) and amnestic mild cognitive impairment (aMCI). However, the question of whether recently acquired knowledge is more impaired than remotely acquired ... -
Memory for public events in mild cognitive impairment and Alzheimer’s disease : the importance of rehearsal
(2016-02-22)Ribot’s law refers to the better preservation of remote memories compared with recent ones that presumably characterizes retrograde amnesia. Even if Ribot-type temporal gradient has been extensively studied in retrograde amnesia, particularly in ... -
A qualitative impairment in face perception in Alzheimer’s disease : evidence from a reduced face inversion effect
face inversion effect in Alzheimer’s disease
(2016-04-12)Prevalent face recognition difficulties in Alzheimer’s disease (AD) have typically been attributed to the underlying episodic and semantic memory impairment. The aim of the current study was to determine if AD patients are also impaired at the perceptual ... -
Reduced rapid eye movement sleep in late middle-aged and older apolipoprotein E ɛ4 allele carriers
(Oxford University Press, 2024-04-18)Study Objectives Apolipoprotein E ɛ4 (APOE4) is the strongest genetic risk factor for Alzheimer’s disease (AD). In addition, APOE4 carriers may exhibit sleep disturbances, but conflicting results have been reported, such that there is no clear consensus ... -
The role of the left anterior temporal lobe for unpredictable and complex mappings in word reading
(Frontiers media, 2017-04)The anterior temporal lobes (ATLs) have been consistently associated with semantic processing which, in turn, has a key role in reading aloud single words. This study aimed to investigate (1) the reading abilities in patients with the semantic variant ... -
Subcortical amyloid load is associated with shape and volume in cognitively normal individuals
Subcortical Aβ associates to morphometry
(Wiley, 2019-05-21)Amyloid-beta (Aβ) deposition is one of the main hallmarks of Alzheimer’s disease. The study assessed the associations between cortical and subcortical 11C-Pittsburgh Compound B retention, namely in the hippocampus, amygdala, putamen, caudate, pallidum, ...