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dc.contributor.authorBaril, Andrée‐Ann
dc.contributor.authorGagnon, Jean‐François
dc.contributor.authorPelletier, Amélie
dc.contributor.authorSoucy, Jean-Paul
dc.contributor.authorGosselin, Nadia
dc.contributor.authorPostuma, Ronald B.
dc.contributor.authorMontplaisir, Jacques-Yves
dc.date.accessioned2020-12-04T15:32:01Z
dc.date.availableNO_RESTRICTIONfr
dc.date.available2020-12-04T15:32:01Z
dc.date.issued2020-05-27
dc.identifier.urihttp://hdl.handle.net/1866/24077
dc.publisherWileyfr
dc.rightsCe document est mis à disposition selon les termes de la Licence Creative Commons Attribution - Pas d’utilisation commerciale 4.0 International. / This work is licensed under a Creative Commons Attribution - NonCommercial 4.0 International License.
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/
dc.subjectRegional cerebral blood flowfr
dc.subjectREM sleep behavior disorderfr
dc.subjectSingle-photon emission computed tomographyfr
dc.subjectSynucleinopathyfr
dc.titleChanges in regional cerebral perfusion over time in idiopathic REM sleep behavior disorderfr
dc.typeArticlefr
dc.contributor.affiliationUniversité de Montréal. Faculté des arts et des sciences. Département de psychologiefr
dc.identifier.doi10.1002/mds.28092
dcterms.abstractBackground Idiopathic rapid eye movement sleep behavior disorder is associated with increased risk of neurodegeneration, but the temporal evolution of regional perfusion, a marker of cerebral activity, has not been characterized. The objective of the current study was to study longitudinal regional perfusion in patients with idiopathic rapid eye movement sleep behavior disorder. Methods Thirty‐seven patients and 23 controls underwent high‐resolution single‐photon emission computed tomography. After 17 months on average, scans were repeated for idiopathic rapid eye movement sleep behavior disorder patients. We compared regional cerebral blood flow between groups and over time. Results At baseline, patients showed lower relative regional perfusion in the anterior frontal and lateral parietotemporal cortex compared with controls. However, over time, patients showed an increase in relative regional perfusion in the anterior frontal, lateral parietal, and occipitotemporal cortex, reverting toward normal control levels. Conclusions Patients with idiopathic rapid eye movement sleep behavior disorder showed significant areas of relative regional hypoperfusion, which disappeared over time to finally return to average levels, suggesting possible developing compensation in areas affected by neurodegeneration.fr
dcterms.isPartOfurn:ISSN:0885-3185fr
dcterms.isPartOfurn:ISSN:1531-8257fr
dcterms.languageengfr
UdeM.ReferenceFournieParDeposantMovement Disorders Wiley PDF de l'éditeur + CC PMID: 32459015 DOI: 10.1002/mds.28092fr
UdeM.VersionRioxxVersion acceptée / Accepted Manuscriptfr
oaire.citationTitleMovement disordersfr
oaire.citationVolume35fr
oaire.citationIssue8fr
oaire.citationStartPage1475fr
oaire.citationEndPage1481fr


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Ce document est mis à disposition selon les termes de la Licence Creative Commons Attribution - Pas d’utilisation commerciale 4.0 International. / This work is licensed under a Creative Commons Attribution - NonCommercial 4.0 International License.
RightsCe document est mis à disposition selon les termes de la Licence Creative Commons Attribution - Pas d’utilisation commerciale 4.0 International. / This work is licensed under a Creative Commons Attribution - NonCommercial 4.0 International License.

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