Browsing Titles index "The dichotomous pattern of IL-12R and IL-23R expression elucidates the role of IL-12 and IL-23 in inflammation"

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  • The dichotomous pattern of IL-12R and IL-23R expression elucidates the role of IL-12 and IL-23 in inflammation 

    Chognard, Gaëlle; Bellemare, Lisa; Pelletier, Adam-Nicolas; Domínguez Punaro, María de la Cruz; Beauchamp, Claudine; Guyon, Marie-Josée; Charron, Guy; Morin, Nicolas; Sivanesan, Durga; Kuchroo, Vijay; Kuchroo, Vijay; Michnick, Stephen; Chemtob, Sylvain; Rioux, John David; Lesage, Sylvie (Public Library of Science, 2014-02-21)
    IL-12 and IL-23 cytokines respectively drive Th1 and Th17 type responses. Yet, little is known regarding the biology of these receptors. As the IL-12 and IL-23 receptors share a common subunit, it has been assumed that these receptors are co-expressed. ...