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  • Portacaval anastomosis-induced hyperammonemia does not lead to oxidative stress 

    Yang, Xiaoling; Bosoi, Cristina R.; Jiang, Wenlei; Tremblay, Mélanie; Rose, Christopher (2010-03)
    Ammonia is neurotoxic and believed to play a major role in the pathogenesis of hepatic encephalopathy (HE). It has been demonstrated, in vitro and in vivo, that acute and high ammonia treatment induces oxidative stress. Reactive oxygen species (ROS) ...