Browsing Titles index "Paternal age explains a major portion of de novo germline mutation rate variability in healthy individuals"

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  • Paternal age explains a major portion of de novo germline mutation rate variability in healthy individuals 

    Girard, Simon L.; Bourassa, Cynthia V.; Lemieux Perreault, Louis-Philippe; Legault, Marc-André; Barhdadi, Amina; Ambalavanan, Amirthagowri; Brendgen, Mara; Vitaro, Frank; Noreau, Anne; Dionne, Ginette; Tremblay, Richard Ernest; Dion, Patrick A.; Boivin, Michel; Dubé, Marie-Pierre; Rouleau, Guy (Public Library of Science, 2016-10-10)
    De novo mutations (DNM) are an important source of rare variants and are increasingly being linked to the development of many diseases. Recently, the paternal age effect has been the focus of a number of studies that attempt to explain the observation ...