Browsing Titles index "Liver international"
Now showing items 1-8 of 8
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2021 ISHEN guidelines on animal models of hepatic encephalopathy
(Wiley, 2021-04-01)This working group of the International Society of Hepatic Encephalopathy and Nitrogen Metabolism (ISHEN) was commissioned to summarize and update current efforts in the development and characterization of animal models of hepatic encephalopathy (HE). ... -
Ammonia: more than a neurotoxin?
(2014) -
Enoxaparin does not ameliorate liver fibrosis or portal hypertension in rats with advanced cirrhosis
(Wiley, 2017-06-30)Background & Aims Recent studies suggest that heparins reduce liver fibrosis and the risk of decompensation of liver disease. Here, we evaluated the effects of enoxaparin in several experimental models of advanced cirrhosis. Methods Cirrhosis was ... -
Genetically engineered E. coli Nissle attenuates hyperammonemia and prevents memory impairment in bile‐duct ligated rats
(Wiley, 2021-02-06)Hyperammonemia associated with chronic liver disease (CLD) is implicated in the pathogenesis of hepatic encephalopathy (HE). The gut is a major source of ammonia production that contributes to hyperammonemia in CLD and HE and remains the primary ... -
Induction of systemic oxidative stress leads to brain oedema in portacaval shunted rats
(Wiley, 2013-11-25)Background & Aims The pathogenesis of hepatic encephalopathy (HE) is multifactorial and often associated with the development of brain oedema. In addition to ammonia playing a central role, systemic oxidative stress is believed to aggravate the ... -
Plasmatic osmolality and hepatic encephalopathy : a new player on the field?
(Wiley, 2020-08-31) -
Progressive resistance training prevents loss of muscle mass and strength in bile duct‐ligated rats
(Wiley, 2018-11-05)BACKGROUND: Loss of muscle mass and strength is common in cirrhosis and increases the risk of hyperammonaemia and hepatic encephalopathy. Resistance training optimizes muscle mass and strength in several chronic diseases. However, the ...