Parcourir l'index des titres "Leukemia"

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  • Comparative small molecule screening of primary human acute leukemias, engineered human leukemia and leukemia cell lines 

    Safa-Tahar-Henni, Safia; Páez Martinez, Karla; Gress, Verena; Esparza, Nayeli; Roques, Élodie; Bonnet-Magnaval, Florence; Bilodeau, Mélanie; Gagné, Valérie; Bresson, Eva; Cardin, Sophie; El-Hachem, Nehme; Iasenza, Isabella; Alzial, Gabriel; Boivin, Isabel; Nakamichi, Naoto; Soufflet, Anne-Cécile; Pascariu, Cristina Mirela; Duchaine, Jean; Mathien, Simon; Bonneil, Eric; Eppert, Kolja; Marinier, Anne; Sauvageau, Guy; Deblois, Geneviève; Thibault, Pierre; Hébert, Josée; Eaves, Connie J.; Cellot, Sonia; Barabé, Frédéric; Wilhelm, Brian (Springer Nature, 2024-07-29)
    Targeted therapeutics for high-risk cancers remains an unmet medical need. Here we report the results of a large-scale screen of over 11,000 molecules for their ability to inhibit the survival and growth in vitro of human leukemic cells from multiple ...