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Frequency of Chromosome Healing and Interstitial Telomeres in 40 Cases of Constitutional Abnormalities
(S. Karger AG, Basel, 2009-09-04)Human telomeres play a major role in stabilizing chromosome ends and preventing fusions. Chromosomes bearing a broken end are rescued by the acquisition of a new telomeric cap without any subtelomeric sequences being present at the breakpoint, a process ...