• Collagen analogs with phosphorylcholine are inflammation-suppressing scaffolds for corneal regeneration from alkali burns in mini-pigs 

    Simpson, Fiona; McTiernan, Christopher D.; Mirazul Islam, Mohammad; Buznyk, Oleksiy; Lewis, Philip N.; Meek, Keith M.; Haagdorens, Michel; Audiger, Cindy; Lesage, Sylvie; Gueriot, François-Xavier; Brunette, Isabelle; Robert, Marie-Claude; Olsen, David; Koivusalo, Laura; Liszka, Aneta; Fagerholm, Per; Gonzalez-Andrades, Miguel; Griffith, May (Nature Research, 2021-05-21)
    The long-term survival of biomaterial implants is often hampered by surgery-induced inflammation that can lead to graft failure. Considering that most corneas receiving grafts are either pathological or inflamed before implantation, the risk of rejection ...
  • Decreased progenitor TCF1 + T-cells correlate with COVID-19 disease severity 

    Tu, Thai Hien; Grunbaum, Ami; François, Santinon; Kazanova, Alexandra; Rozza, Nicholas; Kremer, Richard; Mihalcioiu, Catalin; Rudd, Christopher E. (Nature research, 2024-05-03)
    COVID-19, caused by SARS-CoV-2, can lead to a severe inflammatory disease characterized by significant lymphopenia. However, the underlying cause for the depletion of T-cells in COVID-19 patients remains incompletely understood. In this study, we ...