Now showing items 21-40 of 677

  • Adhesion and transcellular migration of neutrophils and B lymphocytes on fibroblasts 

    Couture, Patrick; Paradis-Massie, Jérémie; Oualha, Nadia; Thibault, Gaétan (2009)
    During tissue inflammation, infiltrated leukocytes may have physical contacts with fibroblasts. We observed that neutrophils and B lymphocytes adhered in a larger proportion than T cells on cultured fibroblasts. Microscopy showed that adhesion was also ...
  • Adipose tissue (P)RR regulates insulin sensitivity, fat mass and body weight 

    Shamansurova Akhmedova, Zulaykho; Tan, Paul; Ahmed, Basma; Pepin, Émilie; Seda, Ondrej; Lavoie, Julie (Elsevier, 2016-08-23)
    Objective We previously demonstrated that the handle-region peptide, a prorenin/renin receptor [(P)RR] blocker, reduces body weight and fat mass and may improve insulin sensitivity in high-fat fed mice. We hypothesized that knocking out the adipose ...
  • The adoption of LI-RADS : a survey of non-academic radiologists 

    Marks, Robert M.; Fung, Alice W.; Cruite, Irene; Blevins, Kasina; Lalani, Tasneem; Horvat, Natally; Protopapas, Zenon; Chaudhry, Humaira; Bijan, Bijan; Shiehmorteza, Masoud; Nepal, Pankaj; Tang, An (Springer, 2023-05-26)
    Purpose: To understand the practice and determinants of non-academic radiologists regarding LIRADS and the four current LI-RADS algorithms: CT/MRI, contrast-enhanced ultrasound (CEUS), ultrasound (US), and CT/MRI Treatment Response. Materials and ...
  • Advancing social inclusion of people with disabilities through awareness and training activities : a collaborative process between community partners and researchers 

    Rochette, Annie; Roberge-Dao, Jacqueline; Roche, Lise; Kehayia, Eva; Ménard, Lyne; Robin, Jean-Pierre; Sauvé, Méric; Shikako-Thomas, Keiko; St-Onge, Marc; Swaine, Bonnie; Thomas, Aliki; Vallée-Dumas, Catherine; Fougeyrollas, Patrick (Elsevier, 2021-05-23)
    Objective The main objectives were to 1) search and map current disability awareness and training activities in Quebec, Canada, 2) collectively reflect on these practices, and 3) develop a five-year strategic plan. Methods We used an integrated ...
  • Albumin dialysis : a new therapeutic strategy for intoxication from protein-bound drugs 

    Sen, Sambit; Ytrebø, Lars M.; Rose, Christopher; Fuskevaag, Ole-Martin; Davies, Nathan A.; Nedredal, Geir I.; Williams, Roger; Revhaug, Arthur; Jalan, Rajiv (Springer, 2004-01-21)
    Abstract Objective: Although water-soluble drugs can be removed by haemofiltration/haemodialysis, morbidity and mortality from intoxication with protein-bound drugs remains high. The present study investigates whether albumin dialysis in the form of ...
  • Algal Biofuels: Challenges and Opportunities 

    Leite, Gustavo Balduino; Abdelaziz, Ahmed E. M.; Hallenbeck, Patrick C. (Elsevier, 2013)
    Biodiesel production using microalgae is attractive in a number of respects. Here a number of pros and cons to using microalgae for biofuels production are reviewed. Algal cultivation can be carried out using non-arable land and non-potable water with ...
  • Altered sensory-weighting mechanisms is observed in adolescents with idiopathic scoliosis 

    Simoneau, Martin; Mercier, Pierre; Blouin, Jean; Allard, Paul; Teasdale, Normand (2006)
    BACKGROUND:Scoliosis is the most common type of spinal deformity. In North American children, adolescent idiopathic scoliosis (AIS) makes up about 90% of all cases of scoliosis. While its prevalence is about 2% to 3% in children aged between 10 to 16 ...
  • Alternative Time Representation in Dopamine Models 

    Rivest, François; Kalaska, John Francis; Bengio, Yoshua (Springer Science + Business Media, 2009)
    Données originales publiées dans l'article: Rivest, F, Kalaska, J.F., Bengio, Y. (2009) Alternative time representation in dopamine models. Journal of Computational Neuroscience. doi:10.1007/s10827-009-0191-1
  • Amino acid substitutions in σ1 and μ1 outer capsid proteins are selected during mammalian reovirus adaptation to Vero cells 

    Jabre, Roland; Sandekian, Véronique; Lemay, Guy (Elsevier, 2013-09)
    Establishment of viral persistence in cell culture has previously led to the selection of mammalian reovirus mutants, although very few of those have been characterized in details. In the present study, reovirus was adapted to Vero cells that, in ...
  • Amino acids substitutions in σ1 and μ1 outer capsid proteins of a Vero cell-adapted mammalian orthoreovirus are required for optimal virus binding and disassembly 

    Sandekian, Véronique; Lemay, Guy (Elsevier, 2015-01-01)
    In a recent study, the serotype 3 Dearing strain of mammalian orthoreovirus was adapted to Vero cells; cells that exhibit a limited ability to support the early steps of reovirus uncoating and are unable to produce interferon as an antiviral response ...
  • Amino acids, ammonia, and hepatic encephalopathy 

    Kroupina, Katerina; Bémeur, Chantal; Rose, Christopher (Elsevier, 2022-04-30)
    Hepatic encephalopathy (HE) is a decline in brain function arising due to liver insufficiency. The liver's diminished capacity to clear ammonia, and the subsequent accumulation of it, is highly implicated in pathogenesis of HE. Ammonia is endogenously ...
  • Ammonia : this is not the end but rather the end of the beginning 

    Weiss, Nicolas; Dam, Gitte; Rose, Christopher (Elsevier, 2018-04)
    Hepatic encephalopathy (HE) represents a wide spectrum of neurological or neuropsychological symptoms caused by liver disease and/or portosystemic shunts. The major role of hyperammonemia in association with systemic inflammation and oxidative stress ...
  • Ammonia toxicity: from head to toe? 

    Dasarathy, Srinivasan; Mookerjee, Rajeshwar P.; Rackayova, Veronika; Rangroo Thrane, Vinita; Vairappan, Balasubramaniyan; Ott, Peter; Rose, Christopher (Springer, 2016-12)
    Ammonia is diffused and transported across all plasma membranes. This entails that hyperammonemia leads to an increase in ammonia in all organs and tissues. It is known that the toxic ramifications of ammonia primarily touch the brain and cause ...
  • Ammonia: more than a neurotoxin? 

    Rose, Christopher (2014)
  • Ammonia‐lowering strategies for the treatment of hepatic encephalopathy 

    Rose, Christopher (Wiley, 2012-08-08)
    Hyperammonemia leads to neurotoxic levels of brain ammonia and is a major factor involved in the pathogenesis of hepatic encephalopathy (HE). Ammonia‐lowering treatments primarily involve two strategies: inhibiting ammonia production and/or increasing ...
  • AnaBench: a Web/CORBA-based workbench for biomolecular sequence analysis 

    Badidi, Elarbi; De Sousa, Cristina; Lang, Franz Bernd; Burger, Gertraud (2003)
    BACKGROUND:Sequence data analyses such as gene identification, structure modeling or phylogenetic tree inference involve a variety of bioinformatics software tools. Due to the heterogeneity of bioinformatics tools in usage and data requirements, ...
  • Analysis of common and rare VPS13C variants in late-onset Parkinson disease 

    Rudakou, Uladzislau; Ruskey, Jennifer A.; Krohn, Lynne; Laurent, Sandra B.; Spiegelman, Dan; Greenbaum, Lior; Yahalom, Gilad; Desautels, Alex; Montplaisir, Jacques-Yves; Fahn, Stanley; Waters, Cheryl; Levy, Oren; Kehoe, Caitlin M.; Narayan, Sushma; Dauvilliers, Yves; Dupré, Nicolas; Hassin-Baer, Sharon; Alcalay, Roy N.; Rouleau, Guy; Fon, Edward A.; Gan-Or, Ziv (Lippincott, Williams and Wilkins, 2020-01-09)
    Objective We aimed to study the role of coding VPS13C variants in a large cohort of patients with lateonset Parkinson disease (PD) (LOPD). Methods VPS13C and its untranslated regions were sequenced using targeted next-generation sequencing in 1,567 ...
  • Analysis of electrocardiograms during atrial fibrillation 

    Jacquemet, Vincent; Van Oosterom, Adriaan; Vesin, Jean-Marc; Kappenberger, Lukas (Institute of electrical and electronics engineers, 2006-11-30)
    The research discussed in this article is motivated by the search for an optimal classification of the different types of atrial fibrillation (AF) on the basis of recorded atrial signals. This would facilitate the selection of an optimal therapy. This ...
  • Analysis of HIV-1 Vpr determinants responsible for cell growth arrest in Saccharomyces cerevisiae 

    Yao, Xiao-Jian; Rougeau, Nicole; Duisit, Ghislaine; Lemay, Julie; Cohen, Éric A. (2004)
    BACKGROUND:The HIV-1 genome encodes a well-conserved accessory gene product, Vpr, that serves multiple functions in the retroviral life cycle, including the enhancement of viral replication in nondividing macrophages, the induction of G2 cell-cycle ...
  • Analysis of scoliosis trunk deformities using ICA 

    Adankon, Mathias M.; Dansereau, Jean; Labelle, Hubert; Cheriet, Farida (2012-07-02)
    This paper describes a method for analyzing scoliosis trunk deformities using Independent Component Analysis (ICA). Our hypothesis is that ICA can capture the scoliosis deformities visible on the trunk. Unlike Principal Component Analysis (PCA), ICA ...