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EEG connectivity across sleep cycles and age
(American academy of sleep medicine, 2019-11-06)
Study Objectives
In young adults, sleep is associated with important changes in cerebral connectivity during the first cycle of non-rapid eye movement (NREM) sleep. Our study aimed to evaluate how electroencephalography ...
Cerebral white matter diffusion properties and free‐water with obstructive sleep apnea severity in older adults
(Wiley, 2020-03-13)
Characterizing the effects of obstructive sleep apnea (OSA) on the aging brain could be key in our understanding of neurodegeneration in this population. Our objective was to assess white matter properties in newly diagnosed ...
Gray matter hypertrophy and thickening with obstructive sleep apnea in middle-aged and older adults
Gray matter increases with obstructive sleep apnea
(American Thoracic Society, 2017-06-01)
Rationale: Obstructive sleep apnea causes intermittent hypoxemia, hemodynamic fluctuations,
and sleep fragmentation, all of which could damage cerebral gray matter that can be indirectly
assessed with neuroimaging.
Objectives: ...
Regional cerebral blood flow during wakeful rest in older subjects with mild to severe obstructive sleep apnea
Cerebral perfusion in OSA
(Oxford University Press, 2015)
Objectives: To evaluate changes in regional cerebral blood flow (rCBF) during wakeful rest in older
subjects with mild to severe obstructive sleep apnea (OSA) and healthy controls, and to identify
markers of OSA severity ...
REM sleep is associated with the volume of the cholinergic basal forebrain in aMCI individuals
(BMC, 2023-09-08)
Background Rapid-eye movement (REM) sleep highly depends on the activity of cholinergic basal forebrain (BF)
neurons and is reduced in Alzheimer’s disease. Here, we investigated the associations between the volume of ...
Reduced rapid eye movement sleep in late middle-aged and older apolipoprotein E ɛ4 allele carriers
(Oxford University Press, 2024-04-18)
Study Objectives
Apolipoprotein E ɛ4 (APOE4) is the strongest genetic risk factor for Alzheimer’s disease (AD). In addition, APOE4 carriers may exhibit sleep disturbances, but conflicting results have been reported, such ...