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Clinical, anatomical and pathological features in the three variants of primary progressive aphasia : a review
(Frontiers media, 2018-08-21)
Primary progressive aphasias (PPA) are neurodegenerative diseases clinically
characterized by an early and relatively isolated language impairment. Three main
clinical variants, namely the nonfluent/agrammatic variant ...
The role of the left anterior temporal lobe for unpredictable and complex mappings in word reading
(Frontiers media, 2017-04)
The anterior temporal lobes (ATLs) have been consistently associated with semantic
processing which, in turn, has a key role in reading aloud single words. This study aimed
to investigate (1) the reading abilities in ...
The role of the hippocampus in the semantic variant of primary progressive aphasia : a resting‐state fcMRI study
(Wiley, 2019-09-09)
The goal of the study was to determine whether the semantic variant of primary progressive aphasia (svPPA) affects the intrinsic connectivity network anchored to left and right anterior hippocampus, but spares the posterior ...
Naming unique entities in the semantic variant of primary progressive aphasia and Alzheimer's disease : Towards a better understanding of the semantic impairment
(Elsevier, 2016-12-07)
While the semantic variant of primary progressive aphasia (svPPA) is characterized by a predominant semantic memory impairment, episodic memory impairments are the clinical hallmark of Alzheimer's disease (AD). However, ...
Differential language network functional connectivity alterations in Alzheimer's disease and the semantic variant of primary progressive aphasia
(Elsevier, 2019-04-03)
Patients with Alzheimer's disease (AD) and semantic variant primary progressive aphasia (svPPA) can present with similar language impairments, mainly in naming. It has been hypothesized that these deficits are associated ...
Altered gray matter structural covariance networks in early stages of Alzheimer's disease
(Oxford University Press, 2015-05-20)
Clinical symptoms observed in Alzheimer's disease (AD) patients may reflect variations within specific large-scale brain networks, modeling AD as a disconnection syndrome. The present magnetic resonance imaging study aims ...
Atrophy in Alzheimer’s disease and semantic dementia : an ALE meta-analysis of voxel-based morphometry studies
(IOS Press, 2016)
Background/Objectives: Alzheimer’s disease (AD) and semantic dementia (SD) have distinct episodic memory profiles
despite the hippocampal atrophy that characterizes both diseases. The aim of this study was to delineate ...
Connected speech features from picture description in Alzheimer's disease: a systematic review
(IOS Press, 2018-08-21)
The language changes that occur over the course of Alzheimer’s disease (AD) can impact communication abilities and have profound functional consequences. Picture description tasks can be used to approximate everyday ...
Connected speech markers of amyloid burden in primary progressive aphasia
(Elsevier, 2021-10-07)
INTRODUCTION
Positron emission tomography (PET) amyloid imaging has become an important part of the diagnostic workup for patients with primary progressive aphasia (PPA) and uncertain underlying pathology. Here, we employ ...
Comprehension of concrete and abstract words in semantic variant primary progressive aphasia and Alzheimer’s disease: a behavioral and neuroimaging study
(2017-04-20)
The aim of this study was to investigate the comprehension of concrete, abstract and abstract emotional words in semantic variant primary progressive aphasia (svPPA), Alzheimer’s disease (AD), and healthy elderly adults ...