Now showing items 1-5 of 5

  • Amyloid burden and white matter hyperintensities mediate age-related cognitive differences 

    Sévigny Dupont, Pénélope; Bocti, Christian; Joannette, Maude; Lavallée, Marie Maxime; Nikelski, Jim; Vallet, Guillaume; Chertkow, Howard; Joubert, Sven (Elsevier, 2019-08)
    This study examined the additive versus synergistic contribution of beta-amyloid (Aβ) and white matter hyperintensities (WMHs) across 7 cognitive domains in 104 cognitively normal older adults. It also measured the extent to which age-related differences ...
  • Evidence of a relation between hippocampal volume, white matter hyperintensities, and cognition in subjective cognitive decline and mild cognitive impairment 

    Caillaud, Marie; Hudon, Carol; Boller, Benjamin; Brambati, Simona Maria; Duchesne, Simon; Lorrain, Dominique; Gagnon, Jean-François; Maltezos, Samantha; Mellah, Samira; Phillips, Natalie; Consortium for the early identification of Alzheimer’s Disease-Quebec; Belleville, Sylvie (Oxford University Press, 2019-10-26)
    Objective: The concepts of mild cognitive impairment (MCI) and subjective cognitive decline (SCD) have been proposed to identify individuals in the early stages of Alzheimer’s disease (AD), or other neurodegenerative diseases. One approach to validate ...
  • Gray matter hypertrophy and thickening with obstructive sleep apnea in middle-aged and older adults 

    Gray matter increases with obstructive sleep apnea
    Baril, Andrée-Ann; Gagnon, Katia; Brayet, Pauline; Montplaisir, Jacques-Yves; De Beaumont, Louis; Carrier, Julie; Lafond, Chantal; L’Heureux, Francis; Gagnon, Jean-François; Gosselin, Nadia (American Thoracic Society, 2017-06-01)
    Rationale: Obstructive sleep apnea causes intermittent hypoxemia, hemodynamic fluctuations, and sleep fragmentation, all of which could damage cerebral gray matter that can be indirectly assessed with neuroimaging. Objectives: To investigate whether ...
  • Regional cerebral blood flow during wakeful rest in older subjects with mild to severe obstructive sleep apnea 

    Cerebral perfusion in OSA
    Baril, Andrée-Ann; Gagnon, Katia; Arbour, Caroline; Soucy, Jean-Paul; Montplaisir, Jacques-Yves; Gagnon, Jean-François; Gosselin, Nadia (Oxford University Press, 2015)
    Objectives: To evaluate changes in regional cerebral blood flow (rCBF) during wakeful rest in older subjects with mild to severe obstructive sleep apnea (OSA) and healthy controls, and to identify markers of OSA severity that predict altered ...
  • La sémantique, la lecture de mots irréguliers et les lobes temporaux antérieurs 

    Semantics, irregular word reading and the anterior temporal lobes
    Bergeron, Sabryna; Pichette, Dominique; Ciquier, Gabrielle C.; Dubé, Catherine; Brambati, Simona Maria; Wilson, Maximiliano A. (Ortho édition, 2014)
    Dans cette recension des écrits nous présentons les résultats d’études comportementales et de neuroimagerie mettant en rapport la sémantique et la lecture de mots irréguliers, ainsi que la sémantique et les lobes temporaux antérieurs (LTA). Plus ...