Parcourir Faculté des arts et des sciences – Département de psychologie - Travaux et publications par sujet "Alzheimer's disease"
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Alzheimer’s disease and memory strength : gradual decline of memory traces as a function of their strength
(2016-03-29)Objective : Episodic memory impairment is at the core of amnestic mild cognitive impair- ment (aMCI) and Alzheimer ’ s disease (AD). The origin of memory deficits may result either from an encoding deficit or from an accelerated decline of the ... -
Amyloid burden and white matter hyperintensities mediate age-related cognitive differences
(Elsevier, 2019-08)This study examined the additive versus synergistic contribution of beta-amyloid (Aβ) and white matter hyperintensities (WMHs) across 7 cognitive domains in 104 cognitively normal older adults. It also measured the extent to which age-related differences ... -
Atrophy, metabolism and cognition in posterior cortical atrophy spectrum based on AD CSF biomarkers
(Elsevier, 2018-10-10)Introduction In vivo clinical, anatomical and metabolic differences between posterior cortical atrophy (PCA) patients presenting with different Alzheimer's disease (AD) cerebrospinal fluid (CSF) biomarkers profiles are still unknown. Methods Twenty-seven ... -
Capacités de réserve et entraînement cognitif dans le vieillissement : similarité des effets protecteurs sur la cognition et le cerveau = Reserve capacity and cognitive training in aging : the similarity of the protective effects on cognition and brain
(John Libbey Eurotext, 2016)La notion de réserve a été proposée pour expliquer l’écart observé chez certains individus entre le degré de leur atteinte cérébrale et son expression sur le plan cognitif. La réserve serait modulée par des facteurs environnementaux tels que le niveau ... -
Differential language network functional connectivity alterations in Alzheimer's disease and the semantic variant of primary progressive aphasia
(Elsevier, 2019-04-03)Patients with Alzheimer's disease (AD) and semantic variant primary progressive aphasia (svPPA) can present with similar language impairments, mainly in naming. It has been hypothesized that these deficits are associated with different brain mechanisms ... -
Naming unique entities in the semantic variant of primary progressive aphasia and Alzheimer's disease : Towards a better understanding of the semantic impairment
(Elsevier, 2016-12-07)While the semantic variant of primary progressive aphasia (svPPA) is characterized by a predominant semantic memory impairment, episodic memory impairments are the clinical hallmark of Alzheimer's disease (AD). However, AD patients also present with ... -
L’utilisation du discours spontané pour le diagnostic précoce de la maladie d’Alzheimer
The use of connected speech in the early diagnosis of Alzheimer's Disease
(John Libbey Eurotext, 2021-10-01)Le trouble cognitif subjectif (TCS) et le trouble cognitif léger (TCL) font partie des phases préclinique et prodromale de la maladie d’Alzheimer (MA), respectivement, et constituent des facteurs de risque de progression vers la MA. Comme des changements ...