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Chitosan hydrogel micro-bio-devices with complex capillary patterns via reactive-diffusive self-assembly
(Elsevier, 2019-08-29)
We present chitosan hydrogel microfluidic devices with self-assembled complex
microcapillary patterns, conveniently formed by a diffusion-reaction process.
These patterns in chitosan hydrogels are formed by a single-step ...
Platelet quiescence in patients with acute coronary syndrome undergoing coronary artery bypass graft surgery
(Wiley, 2021)
BACKGROUND: The optimal antiplatelet strategy for patients with acute coronary syndromes who require coronary artery
bypass surgery remains unclear. While a more potent antiplatelet regimen will predispose to perioperative ...
Advances in platelet function testing—light transmission aggregometry and beyond
(MDPI, 2020-08-13)
Platelet function testing is essential for the diagnosis of hemostasis disorders. While there
are many methods used to test platelet function for research purposes, standardization is often
lacking, limiting their use ...
The brain-derived neurotrophic factor prompts platelet aggregation and secretion
(American Society of Hematology, 2021-09-21)
Brain-derived neurotrophic factor (BDNF) has both autocrine and paracrine roles in
neurons, and its release and signaling mechanisms have been extensively studied in the
central nervous system. Large quantities of BDNF ...
Start small : how nanomedicine could alleviate the burden of rare CNS Diseases
(MDPI, 2021-01-30)
The complexity and organization of the central nervous system (CNS) is widely modulated by the presence of the blood–brain barrier (BBB) and the blood–cerebrospinal fluid barrier
(BCSFB), which both act as biochemical, ...
A tutorial on dealing with time‐varying eligibility for treatment: Comparing the risk of major bleeding with direct‐acting oral anticoagulants vs warfarin
(Wiley, 2020-08-18)
In this tutorial, we focus on the problem of how to define and estimate treatment
effects when some patients develop a contraindication and are thus ineligible to receive
a treatment of interest during follow-up. We first ...
Impact of discretization of the timeline for longitudinal causal inference methods
(Wiley, 2020-09-01)
In longitudinal settings, causal inference methods usually rely on a
discretization of the patient timeline that may not reflect the underlying data generation process. This paper investigates the estimation of
causal ...
Tissue-specificity of antibodies raised against TrkB and p75NTR receptors ; implications for platelets as models of neurodegenerative diseases
(Frontiers media, 2021-02-11)
Platelets and neurons share many similarities including comparable secretory granule
types with homologous calcium-dependent secretory mechanisms as well as
internalization, sequestration and secretion of many ...
A meta-analysis of the effect of paper versus digital reading on reading comprehension in health professional education
(American Association of Colleges of Pharmacy, 2021-12-29)
Objective. Despite a rise in the use of digital education in health professional education (HPE), little is
known about the comparative effectiveness of paper-based reading and its digital alternative on reading
comprehension. ...
Prescription channeling of COX-2 inhibitors and traditional nonselective nonsteroidal anti-inflammatory drugs: a population-based case–control study
(2005)
This pharmacoepidemiologic study was conducted to determine whether risk factors for upper gastrointestinal bleeding influenced the prescription of cyclo-oxygenase (COX)-2 inhibitors and traditional nonselective nonsteroidal ...