Prospective associations between meth/amphetamine (speed) and MDMA (ecstasy) use and depressive symptoms in secondary school students
dc.contributor.author | Nault-Brière, Frédéric | |
dc.contributor.author | Fallu, Jean-Sébastien | |
dc.contributor.author | Janosz, Michel | |
dc.contributor.author | Pagani, Linda S. | |
dc.date.accessioned | 2016-05-30T16:42:12Z | |
dc.date.available | NO_RESTRICTION | fr |
dc.date.available | 2016-05-30T16:42:12Z | |
dc.date.issued | 2012-11 | |
dc.identifier.uri | http://hdl.handle.net/1866/13923 | |
dc.subject | MDMA | fr |
dc.subject | Methamphetamine | fr |
dc.subject | Depression | fr |
dc.subject | Adolescence | fr |
dc.subject | Longitudinal | fr |
dc.title | Prospective associations between meth/amphetamine (speed) and MDMA (ecstasy) use and depressive symptoms in secondary school students | fr |
dc.type | Article | |
dc.contributor.affiliation | Université de Montréal. Faculté des arts et des sciences. École de psychoéducation | fr |
UdeM.statut | Professeur(e) / Professor | fr |
dc.identifier.doi | 10.1136/jech-2011-200706 | |
dcterms.abstract | Background Research has raised significant concern regarding the affective consequences of synthetic drug use. However, little evidence from well-controlled longitudinal studies exists on these consequences. The aim of this study was to determine whether use of meth/amphetamine (speed) and 63,4- methylenedioxymethamphetamine (MDMA, ecstasy) is independently predictive of subsequent depressive symptoms in adolescents. Methods A sample of 3880 adolescents from secondary schools in disadvantaged areas of Quebec, Canada, were followed over time (2003e2008). Logistic regression was used to test the association between meth/ amphetamine and MDMA use in grade 10 (ages 15e16 years) and elevated depressive symptoms on an abridged Center for Epidemiologic Studies-Depression scale in grade 11, controlling for pre-existing individual and contextual characteristics. Results After adjustment, both MDMA use (OR 1.7, 95% CI 1.1 to 2.6) and meth/amphetamine use (OR 1.6, 95% CI 1.1 to 2.3) in grade 10 significantly increased the odds of elevated depressive symptoms in grade 11. These relationships did not vary by gender or pre-existing depressive symptoms. Increased risk was particularly observed in concurrent usage (OR 1.9, 95% CI 1.2 to 2.9). Conclusions Adolescent use of meth/amphetamine and MDMA (particularly concurrent use) is independently associated with subsequent depressive symptoms. Further enquiry must determine whether these associations reflect drug-induced neurotoxicity and whether adolescence is a period of increased vulnerability to the hazards of synthetic drug exposure. | fr |
dcterms.isPartOf | urn:ISSN:1470-2738 | |
dcterms.isPartOf | urn:ISSN:0143-005X | |
dcterms.language | eng | fr |
UdeM.VersionRioxx | Version originale de l'auteur·e / Author's Original | |
oaire.citationTitle | Journal of epidemiology and community health | |
oaire.citationVolume | 66 | |
oaire.citationIssue | 11 | |
oaire.citationStartPage | 990 | |
oaire.citationEndPage | 994 |
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