Search
Now showing items 61-70 of 113
Unusual central nervous system lesions in slaughter-weight pigs with porcine circovirus type 2 systemic infection
(2011-04)
Lésions inhabituelles au système nerveux central chez des porcs au poids d’abattage atteints d’une
infection systémique par le circovirus porcin type 2. Une infection systémique par le circovirus porcin type 2
fut ...
Liquid Chromatography-Electrospray Linear Ion Trap Mass Spectrometry Analysis of Targeted Neuropeptides in Tac1-/- Mouse Spinal Cords Reveal Significant Lower Concentration of Opioid Peptides
(2015-08)
Tachykinin and opioid peptides play a central role in pain transmission, modulation and
inhibition. The treatment of pain is very important in medicine and many studies using NK1
receptor antagonists failed to show ...
Eucaryotic Expression of the Nucleocapsid Protein Gene of Porcine Circovirus Type 2 and Use of the Protein in an Indirect Immunofluorescence Assay for Serological Diagnosis of Postweaning Multisystemic Wasting Syndrome in Pigs
(2004-07)
The purpose of this study was to develop a sensitive, rapid, and inexpensive immunofluorescence assay (IFA) using a recombinant porcine circovirus type 2 (PCV2) nucleocapsid protein for the serological detection of ...
Alternative codon usage of PRRS virus ORF5 gene increases eucaryotic expression of GP5 glycoprotein and improves immune response in challenged pigs
(2005-07)
Pigs exposed to GP5 protein of PRRSV by means of DNA immunization develop specific neutralizing and protecting antibodies. Herein, we
report on the consequences of codon bias, and on the favorable outcome of the systematic ...
Assessment of Tandem Mass Spectrometry and High Resolution Mass Spectrometry for the Analysis of Bupivacaine in Plasma
(2015-11-01)
Triple quadrupole mass spectrometers coupled with high performance liquid chromatography are
workhorses in quantitative bioanalyses. It provides substantial benefits including reproducibility,
sensitivity and selectivity ...
In Vitro Ketamine CYP3A Mediated Metabolism Study using Mammalian Liver S9 Fractions, cDNA Expressed Enzymes and Liquid Chromatography Tandem Mass Spectrometry
(2014-12-01)
Ketamine is widely used in medicine in combination with several benzodiazepines including
midazolam. The objectives of this study were to develop a novel HPLC-MS/SRM method
capable of quantifying ketamine and norketamine ...
Microtubule disrupting N-phenyl-N’-(2-chloroethyl) ureas display anticancer activity on cell adhesion, P-glycoprotein and BCL-2-mediated drug resistance
(2014-04)
Objective: Our research program has focused on the development of promising, soft alkylating N-phenyl-N’-(2-chloroethyl)urea (CEU) compounds
which acylate the glutamic acid-198 of β-tubulin, near the binding site of ...
Evaluation of multiple reaction monitoring cubed for the analysis of tachykinin related peptides in rat spinal cord using a hybrid triple quadrupole–linear ion trap mass spectrometer
(2014-02)
Targeted peptide methods generally use HPLC-MS/MRM approaches. Although dependent on
the instrumental resolution, interferences may occur while performing analysis of complex
biological matrices. HPLC-MS/MRM3 is a ...
Emergence of a New Swine H3N2 and Pandemic (H1N1) 2009 Influenza A Virus Reassortant in Two Canadian Animal Populations, Mink and Swine
(2011-12)
A swine H3N2 (swH3N2) and pandemic (H1N1) 2009 (pH1N1) influenza A virus reassortant (swH3N2/
pH1N1) was detected in Canadian swine at the end of 2010. Simultaneously, a similar virus was also detected
in Canadian mink ...
High-throughput sequencing revealed the presence of an unforeseen parvovirus species in Canadian swine : the porcine partetravirus
Cross Canada disease report = Rapport des maladies diagnostiquées au Canada
(2013-08-01)