dc.contributor.author | Guimont-Desrochers, Fanny | |
dc.contributor.author | Lesage, Sylvie | |
dc.date.accessioned | 2023-01-25T18:16:03Z | |
dc.date.available | NO_RESTRICTION | fr |
dc.date.available | 2023-01-25T18:16:03Z | |
dc.date.issued | 2013-12-11 | |
dc.identifier.uri | http://hdl.handle.net/1866/27361 | |
dc.publisher | Frontiers Media | fr |
dc.rights | Ce document est mis à disposition selon les termes de la Licence Creative Commons
Paternité 3.0 non transposé / License Creative Commons Attribution 3.0 Unported | |
dc.rights.uri | https://creativecommons.org/licenses/by/3.0/deed.fr | |
dc.subject | Natural killer cells | fr |
dc.subject | Cellular differentiation | fr |
dc.subject | Pre-mNK cells | fr |
dc.subject | Anti-tumoral activity | fr |
dc.subject | Human | fr |
dc.subject | Mouse | fr |
dc.title | Revisiting the prominent anti-tumoral potential of pre-mNK cells | fr |
dc.type | Article | fr |
dc.contributor.affiliation | Université de Montréal. Faculté de médecine. Département de microbiologie, infectiologie et immunologie | fr |
dc.identifier.doi | 10.3389/fimmu.2013.00446 | |
dcterms.abstract | Interferon-producing killer dendritic cells (IKDC) were first described for their outstanding
anti-tumoral properties.The “IKDC” terminology implied the description of a novel DC subset and initiated a debate on their cellular lineage origin.This debate shifted the focus away
from their notable anti-tumoral potential. IKDC were recently redefined as precursors to
mature NK (mNK) cells and consequently renamed pre-mNK cells. Importantly, a putative
human equivalent of pre-mNK cells was recently associated with improved disease outcome in cancer patients. It is thus timely to revisit the functional attributes as well as the
therapeutic potential of pre-mNK cells in line with their newly defined NK-cell precursor
function. | fr |
dcterms.isPartOf | urn:ISSN:1664-3224 | fr |
dcterms.language | eng | fr |
UdeM.ReferenceFournieParDeposant | 10.3389/fimmu.2013.00446 | fr |
UdeM.VersionRioxx | Version publiée / Version of Record | fr |
oaire.citationTitle | Frontiers in immunology | fr |
oaire.citationVolume | 4 | fr |