Browsing Faculté de médecine – Travaux et publications by Subject "Genetics"
Now showing items 1-5 of 5
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The dementia-associated APOE ε4 allele is not associated with REM sleep behavior disorder
(Elsevier, 2016-10-13)The present study aimed to examine whether the APOE ε4 allele, associated with dementia with Lewy bodies (DLB), and possibly with dementia in Parkinson's disease (PD), is also associated with idiopathic rapid eye movement sleep behavior disorder (RBD). ... -
Developmental origins of chronic physical aggression: an international perspective on using singletons, twins and epigenetics
(SAGE, 2015-09-08)This chapter takes an international and historical perspective to discuss the present state of knowledge on the developmental origins of physical aggression and its implications for the prevention of chronic physical aggression. An increasing number ... -
Genetic markers of Restless Legs Syndrome in Parkinson disease
(Elsevier, 2015-06)INTRODUCTION: Several studies proposed that Restless Legs Syndrome (RLS) and Parkinson disease (PD) may be clinically and/or etiologically related. To examine this hypothesis, we aimed to determine whether the known RLS genetic markers may be associated ... -
Genomic architecture of human neuroanatomical diversity
(Nature Publishing Group, 2015-08)Human brain anatomy is strikingly diverse and highly inheritable: genetic factors may explain up to 80% of its variability. Prior studies have tried to detect genetic variants with a large effect on neuroanatomical diversity, but those currently ... -
The role of the melanoma gene MC1R in Parkinson disease and REM sleep behavior disorder
(Elsevier, 2016-07)The MC1R gene, suggested to be involved in Parkinson disease (PD) and melanoma, was sequenced in PD patients (n=539) and controls (n=265) from New-York, and PD patients (n=551), rapid eye movement sleep behavior disorder (RBD) patients (n=351) and ...