Browsing Faculté de médecine – Travaux et publications by Subject "Genetic susceptibility"
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Bisphosphoglycerate mutase deficiency protects against cerebral malaria and severe malaria-induced anemia
(Cell Press, 2020-09-22)The replication cycle and pathogenesis of the Plasmodium malarial parasite involves rapid expansion in red blood cells (RBCs), and variants of certain RBC-specific proteins protect against malaria in humans. In RBCs, bisphosphoglycerate mutase (BPGM) ...