Browsing Faculté de médecine – Travaux et publications by Author "Quinou, Christiane"
Now showing items 1-1 of 1
-
IL23R (Interleukin 23 Receptor) variants protective against inflammatory bowel diseases (IBD) display loss of functiondue to impaired protein stability and intracellular trafficking
Sivanesan, Durga; Beauchamp, Claudine; Quinou, Christiane; Lee, Jonathan; Lesage, Sylvie; Chemtob, Sylvain; Rioux, John David; Michnick, Stephen (Elsevier, 2016)Genome-wide association studies as well as murine models have shown that the interleukin 23 receptor (IL23R) pathway plays a pivotal role in chronic inflammatory diseases such as Crohn disease (CD), ulcerative colitis, psoriasis, and type 1 diabetes. ...