Browsing Faculté de médecine – Travaux et publications by Author "Li, Yuanyi"
Now showing items 1-1 of 1
-
Flt3L-Mediated expansion of plasmacytoid dendritic cells suppresses HIV infection in humanized mice
Pham, Tram N.Q.; Meziane, Oussama; Miah, Mohammad Alam; Volodina, Olga; Colas, Chloé; Béland, Kathie; Li, Yuanyi; Dallaire, Frédéric; Keler, Tibor; Guimond, Jean V.; Lesage, Sylvie; Cheong, Cheolho; Haddad, Elie; Cohen, Éric A. (Cell Press, 2019-11-26)Plasmacytoid dendritic cells (plasmacytoid DC, pDC) are major IFN-I producers and have been shown to be affected by HIV through ill-defined mechanisms. In this study, we directly assess the role of pDC in early infection, evaluating whether modulating ...