Browsing Faculté de médecine – Travaux et publications by Author "Kleinman, Claudia"
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A maximum likelihood framework for protein design
Kleinman, Claudia; Rodrigue, Nicolas; Bonnard, Cécile; Philippe, Hervé; Lartillot, Nicolas (2006)BACKGROUND:The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, this problem can also be understood in a wider context, where additional ...