Browsing Faculté de médecine – Travaux et publications by Author "Jacques, Pierre-Étienne"

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  • The euchromatic and heterochromatic landscapes are shaped by antagonizing effects of transcription on H2A.Z deposition 

    Hardy, Sara; Jacques, Pierre-Étienne; Gévry, Nicolas; Forest, Audrey; Fortin, Marie-Ève; Laflamme, Liette; Gaudreau, Luc; Robert, François (2009)
    A role for variant histone H2A.Z in gene expression is now well established but little is known about the mechanisms by which it operates. Using a combination of ChIP-chip, knockdown and expression profiling experiments, we show that upon gene induction, ...

  • Yeast RNase III triggers polyadenylation-independent transcription termination 

    Ghazal, Ghada; Gagnon, Jules; Jacques, Pierre-Étienne; Landry, Josette-Renée; Robert, François; Abou Elela, Sherif (2009)
    Transcription termination of messenger RNA (mRNA) is normally achieved by polyadenylation followed by Rat1p-dependent 5'-3' exoribonuleolytic degradation of the downstream transcript. Here we show that the yeast ortholog of the dsRNA-specific ribonuclease ...