Browsing Faculté de médecine – Travaux et publications by Author "Jacquemet, Vincent"
Now showing items 1-20 of 35
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Analysis of electrocardiograms during atrial fibrillation
Jacquemet, Vincent; Van Oosterom, Adriaan; Vesin, Jean-Marc; Kappenberger, Lukas (Institute of electrical and electronics engineers, 2006-11-30)The research discussed in this article is motivated by the search for an optimal classification of the different types of atrial fibrillation (AF) on the basis of recorded atrial signals. This would facilitate the selection of an optimal therapy. This ... -
Assessment of the sensitivity of detecting drug-induced QTc changes using subject-specific rate correction
Cassani González, Raymundo; Engels, Elien B.; Dubé, Bruno; Nadeau, Reginald; Vinet, Alain; Leblanc, Aime Robert; Sturmer, Marcio; Becker, Giuliano; Kus, Térésa; Jacquemet, Vincent (Elsevier, 2012)Aims To quantify the sensitivity of QT heart-rate correction methods for detecting drug-induced QTc changes in thorough QT studies. Methods Twenty-four-hour Holter ECGs were analyzed in 66 normal subjects during placebo and moxifloxacin delivery ... -
Cancellation of ventricular activity in the ECG : evaluation of novel and existing methods
Lemay, Mathieu; Vesin, Jean-Marc; Van Oosterom, Adriaan; Jacquemet, Vincent; Kappenberger, Lukas (Institute of electrical and electronics engineers, 2007-02-20)Due to the much higher amplitude of the electrical activity of the ventricles in the surface electrocardiogram (ECG), its cancellation is crucial for the analysis and characterization of atrial fibrillation. In this paper, two different methods are ... -
The effect of tissue geometry on the activation recovery interval of atrial myocytes
Van Oosterom, Adriaan; Jacquemet, Vincent (Elsevier, 2008-08-13)The propagation of electric activity inside a realistically-shaped, thick-walled model of the atria was studied. The membrane kinetics was based on the formulations of Courtemanche, Ramirez and Nattel. In spite of the assumed uniformity of all ... -
An eikonal approach for the initiation of reentrant cardiac propagation in reaction-diffusion models
Jacquemet, Vincent (Institute of electrical and electronics engineers, 2010-05-27)Microscale electrical propagation in the heart can be modeled by a reaction-diffusion system describing cell and tissue electrophysiology. Macroscale features of wavefront propagation can be reproduced by an eikonal model, a reduced formulation involving ... -
Eikonal equation : computation
Jacquemet, Vincent (Springer, 2015) -
Eikonal-based initiation of fibrillatory activity in thin-walled cardiac propagation models
Herlin, Antoine; Jacquemet, Vincent (American Institute of Physics, 2011-12-22)Reentrant arrhythmias can be simulated in electrophysiological models of electrical impulse propagation governed by a reaction-diffusion system. To facilitate the initiation of a large number of independent episodes of simulated arrhythmias with ... -
An eikonal-diffusion solver and its application to the interpolation and the simulation of reentrant cardiac activations
Jacquemet, Vincent (Elsevier, 2012)Electrical propagation of the cardiac impulse in the myocardium can be described by the eikonal-diffusion equation. This equation governs the field of activation times in a domain where conduction properties are specified. This approach has been applied ... -
Equivalent dipole sources to estimate the influence of extracellular myocardial anisotropy in thin-walled cardiac forward models
Jacquemet, Vincent (Elsevier, 2017)The extracellular domain of the heart is anisotropic, which affects volume conduction and therefore body surface potentials. This paper tests the hypothesis that when wall thickness is sufficiently small (such as in the atria), the effect of extracellular ... -
Estimation of the QT-RR relation : trade-off between goodness-of-fit and extrapolation accuracy
Vinet, Alain; Dubé, Bruno; Nadeau, Réginald; Mahiddine, Omar; Jacquemet, Vincent (IOP Publishing, 2017-02-03)Correction of the QT interval in the ECG for changes in heart rate (RR interval) is needed to compare groups of patients and assess the risk of sudden cardiac death. The QTc represents the QT interval at 60 bpm, although most patients typically have a ... -
Evaluation of a subject-specific transfer-function-based nonlinear QT interval rate-correction method
Jacquemet, Vincent; Dubé, Bruno; Knight, Robin; Nadeau, Réginald; LeBlanc, A. Robert; Sturmer, Marcio; Becker, Giuliano; Vinet, Alain; Kuś, Teresa (IOP Publishing, 2011-04-15)The QT interval in the electrocardiogram (ECG) is a measure of total duration of depolarization and repolarization. Correction for heart rate is necessary to provide a single intrinsic physiological value that can be compared between subjects and within ... -
Extraction and analysis of T waves in electrocardiograms during atrial flutter
Jacquemet, Vincent; Dubé, Bruno; Nadeau, Réginald; Leblanc, Aimé Robert; Sturmer, Marcio; Giuliano, Becker; Kus, Térésa; Vinet, Alain (Institute of electrical and electronics engineers, 2010-12-13)Analysis of T waves in the electrocardiogram (ECG) is an essential clinical tool for diagnosis, monitoring and followup of patients with heart dysfunction. During atrial flutter, this analysis has been so far limited by the perturbation of flutter waves ... -
Finite volume stiffness matrix for solving anisotropic cardiac propagation in 2-D and 3-D unstructured meshes
Jacquemet, Vincent; Henriquez, Craig S. (Institute of electrical and electronics engineers, 2005-07-11)The finite volume method (FVM) has been shown recently to be an effective method for discretizing the reaction-diffusion equations that govern wavefront propagation in anisotropic cardiac tissue, as it can naturally handle both complex geometries and ... -
Fitting local repolarization parameters in cardiac reaction-diffusion models in the presence of electrotonic coupling
Aswath Kumar, Akshay Kota; Drahi, Angelina; Jacquemet, Vincent (Elsevier, 2017)Background: Repolarization gradients contribute to arrhythmogenicity. In reaction–diffusion models of cardiac tissue, heterogeneities in action potential duration (APD) can be created by locally modifying an intrinsic membrane kinetics parameter. ... -
Geometrical measurement of cardiac wavelength in reaction-diffusion models
Dupraz, Marie; Jacquemet, Vincent (American Institute of Physics, 2014)The dynamics of reentrant arrhythmias often consists in multiple wavelets propagating throughout an excitable medium. An arrhythmia can be sustained only if these reentrant waves have a sufficiently short wavelength defined as the distance traveled ... -
Modeling atrial arrhythmias : impact on clinical diagnosis and therapies
Jacquemet, Vincent; Kappenberger, Lukas; Henriquez, Craig S. (Institute of electrical and electronics engineers, 2008)Atrial arrhythmias are the most frequent sustained rhythm disorders in humans and often lead to severe complications such as heart failure and stroke. Despite the important insights provided by animal models into the mechanisms of atrial arrhythmias, ... -
Modeling atrial fibrillation : from myocardial cells to ECG
Modeling AF : from myocardial cells to ECG
Van Oosterom, Adriaan; Jacquemet, Vincent (Springer, 2008) -
Modeling left and right atrial contributions to the ECG : a dipole-current source approach
Jacquemet, Vincent (Elsevier, 2015)This paper presents the mathematical formulation, the numerical validation and several illustrations of a forward-modeling approach based on dipole-current sources to compute the contribution of a part of the heart to the electrocardiogram (ECG). ... -
Modeling of atrial fibrillation
Virag, Nathalie; Jacquemet, Vincent; Kappenberger, Lukas (Wiley, 2012-12-18)Computer modeling of atrial fibrillation (AF) is considered today as a potentially effective tool for better understanding AF mechanisms and for the development of therapeutic options. Computer models are based on an integrative approach, from the ... -
Multiparameter optimization of nonuniform passive diffusion properties for creating coarse-grained equivalent models of cardiac propagation
Irakoze, Éric; Jacquemet, Vincent (Elsevier, 2021-09-10)The arrhythmogenic role of discrete cardiac propagation may be assessed by comparing discrete (fine-grained) and equivalent continuous (coarse-grained) models. We aim to develop an optimization algorithm for estimating the smooth conductivity field ...