Now showing items 1-5 of 5

  • BDNF Val66Met polymorphism interacts with sleep consolidation to predict ability to create new declarative memories 

    Gosselin, Nadia; De Beaumont, Louis; Gagnon, Katia; Baril, Andrée-Ann; Mongrain, Valérie; Blais, Hélène; Montplaisir, Jacques-Yves; Gagnon, Jean-François; Pelleieux, Sandra; Poirier, Judes; Carrier, Julie (Society for Neuroscience, 2016-08)
    It is hypothesized that a fundamental function of sleep is to restore an individual's day-to-day ability to learn and to constantly adapt to a changing environment through brain plasticity. Brain-derived neurotrophic factor (BDNF) is among the key ...
  • The dementia-associated APOE ε4 allele is not associated with REM sleep behavior disorder 

    Gan-Or, Ziv; Montplaisir, Jacques-Yves; Ross, Jay P.; Poirier, Judes; Warby, Simon; Arnulf, Isabelle; Strong, Stephanie; Dauvilliers, Yves; Leblond, Claire S.; Hu, Michele T. M.; Högl, Birgit; Stefani, Ambra; Monaca, Christelle; Cochen De Cock, Valérie; Boivin, Michel; Ferini-Strambi, Luigi; Plazzi, Giuseppe; Antelmi, Elena; Young, Peter; Heidbreder, Anna; Barber, Thomas R; Evetts, Samuel G.; Rolinski, Michal; Dion, Patrick A.; Desautels, Alex; Gagnon, Jean-François; Dupré, Nicolas; Postuma, Ronald B.; Rouleau, Guy (Elsevier, 2016-10-13)
    The present study aimed to examine whether the APOE ε4 allele, associated with dementia with Lewy bodies (DLB), and possibly with dementia in Parkinson's disease (PD), is also associated with idiopathic rapid eye movement sleep behavior disorder (RBD). ...
  • GBA mutations are associated with Rapid eye movement sleep behavior disorder 

    Gan-Or, Ziv; Mirelman, Anat; Postuma, Ronald B.; Arnulf, Isabelle; Bar-Shira, Anat; Dauvilliers, Yves; Desautels, Alex; Gagnon, Jean-François; Leblond, Claire S.; Frauscher, Birgit; Alcalay, Roy N.; Saunders-Pullman, Rachel; Bressman, Susan B.; Marder, Karen; Monaca, Christelle; Högl, Birgit; Orr-Urtreger, Avi; Dion, Patrick A.; Montplaisir, Jacques-Yves; Giladi, Nir; Rouleau, Guy (Wiley, 2015-07-31)
    Rapid eye movement sleep behavior disorder and GBA mutations are both associated with Parkinson’s disease. The GBA gene was sequenced in idiopathic rapid eye movement sleep behavior disorder patients (n = 265), and compared to controls (n = 2240). Rapid ...
  • Insomnia and somnolence in idiopathic RBD : a prospective cohort study 

    Postuma, Ronald B.; Gagnon, Jean-François; Pelletier, Amélie; Montplaisir, Jacques-Yves (Nature research, 2017-03-20)
    Although some sleep disorders are markers of prodromal Parkinson’s disease and dementia with Lewy bodies, it is unclear whether insomnia and somnolence can predict disease. We assessed a large cohort of patients with idiopathic rapid eye movement ...
  • The role of the melanoma gene MC1R in Parkinson disease and REM sleep behavior disorder 

    Gan-Or, Ziv; Mohsin, Noreen; Girard, Simon L.; Montplaisir, Jacques-Yves; Ambalavanan, Amirthagowri; Strong, Stephanie; Mallett, Victoria; Laurent, Sandra B.; Bourassa, Cynthia V.; Boivin, Michel; Langlois, Melanie; Arnulf, Isabelle; Högl, Birgit; Frauscher, Birgit; Monaca, Christelle; Desautels, Alex; Gagnon, Jean-François; Postuma, Ronald B.; Dion, Patrick A.; Dauvilliers, Yves; Dupré, Nicolas; Alcalay, Roy N.; Rouleau, Guy (Elsevier, 2016-07)
    The MC1R gene, suggested to be involved in Parkinson disease (PD) and melanoma, was sequenced in PD patients (n=539) and controls (n=265) from New-York, and PD patients (n=551), rapid eye movement sleep behavior disorder (RBD) patients (n=351) and ...