Browsing Faculté de médecine – Travaux et publications by Author "Dupuy, Franck P."

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  • LILAC pilot study : effects of metformin on mTOR activation and HIV reservoir persistence during antiretroviral therapy 

    Planas, Delphine; Pagliuzza, Amélie; Ponte, Rosalie; Fert, Augustine; Raymond Marchand, Laurence; Massanella, Marta; Gosselin, Annie; Mehraj, Vikram; Dupuy, Franck P.; Isnard, Stephane; Goulet, Jean-Philippe; Lesage, Sylvie; Cohen, Éric A.; Ghali, Mager Peter; Angel, Jonathan B.; Chomont, Nicolas; Routy, Jean-Pierre; Ancuta, Petronela (Elsevier, 2021-03-01)
    Background: Chronic inflammation and residual HIV transcription persist in people living with HIV (PLWH) receiving antiretroviral therapy (ART), thus increasing the risk of developing non-AIDS co-morbidities. The mechanistic target of rapamycin (mTOR) ...