Browsing Faculté de médecine – Travaux et publications by Author "Dallaire, Frédéric"

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  • Flt3L-Mediated expansion of plasmacytoid dendritic cells suppresses HIV infection in humanized mice 

    Pham, Tram N.Q.; Meziane, Oussama; Miah, Mohammad Alam; Volodina, Olga; Colas, Chloé; Béland, Kathie; Li, Yuanyi; Dallaire, Frédéric; Keler, Tibor; Guimond, Jean V.; Lesage, Sylvie; Cheong, Cheolho; Haddad, Elie; Cohen, Éric A. (Cell Press, 2019-11-26)
    Plasmacytoid dendritic cells (plasmacytoid DC, pDC) are major IFN-I producers and have been shown to be affected by HIV through ill-defined mechanisms. In this study, we directly assess the role of pDC in early infection, evaluating whether modulating ...