Parcourir Faculté de médecine – Travaux et publications par auteur·e "Cardinal, Héloïse"

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  • The 20S proteasome core, active within apoptotic exosome-like vesicles, induces autoantibody production and accelerates rejection 

    Dieudé, Mélanie; Bell, Christina; Turgeon, Julie; Beillevaire, Déborah; Yang, Bing; Hamelin, Katia; Qi, Shijie; Pallet, Nicolas; Béland, Chanel; Dhahri, Wahiba; Cailhier, Jean-François; Rousseau, Matthieu; Duchez, Anne-Claire; Lévesque, Tania; Lau, Arthur; Rondeau, Christiane; Gingras, Diane; Muruve, Danie; Rivard, Alain; Cardinal, Héloïse; Perreault, Claude; Desjardins, Michel; Boilard, Éric; Thibault, Pierre; Hébert, Marie-Josée (American Association for the Advancement of Science, 2015-12-16)
    Autoantibodies to components of apoptotic cells, such as anti-perlecan antibodies, contribute to rejection in organ transplant recipients. However, mechanisms of immunization to apoptotic components remain largely uncharacterized. We used large-scale ...

  • Caspase-3 dependent peritubular capillary dysfunction is pivotal for transition from acute to chronic kidney disease after acute ischemia-reperfusion injury 

    Lan, Shanshan; Yang, Bing; Migneault, Francis; Turgeon, Julie; Bourgault, Maude; Dieudé, Mélanie; Cardinal, Héloïse; Hickey, Michael; Patey, Natacha; Hébert, Marie-Josée (American Physiological Society, 2021-08-02)
    Ischemia-reperfusion injury (IRI) is a major risk factor for chronic renal failure. Caspase-3, an effector responsible for apoptosis execution, is activated within peritubular capillary (PTC) in the early stage of IRI-induced acute kidney injury (AKI). ...