Parcourir Faculté de médecine – Travaux et publications par sujet "Thorough QT study"

Voici les éléments 1-1 de 1

  • Assessment of the sensitivity of detecting drug-induced QTc changes using subject-specific rate correction 

    Cassani González, Raymundo; Engels, Elien B.; Dubé, Bruno; Nadeau, Reginald; Vinet, Alain; Leblanc, Aime Robert; Sturmer, Marcio; Becker, Giuliano; Kus, Térésa; Jacquemet, Vincent (Elsevier, 2012)
    Aims To quantify the sensitivity of QT heart-rate correction methods for detecting drug-induced QTc changes in thorough QT studies. Methods Twenty-four-hour Holter ECGs were analyzed in 66 normal subjects during placebo and moxifloxacin delivery ...