• Immunoregulatory CD4-CD8- T cells as a potential therapeutic tool for transplantation, autoimmunity, and cancer 

    Hillhouse, Erin; Delisle, Jean-Sébastien; Lesage, Sylvie (Frontiers media, 2013-01-13)
    A central objective in organ transplantation and the treatment or prevention of autoimmune disease is the achievement of antigen-specific immune tolerance. An additional challenge in bone marrow transplantation for the treatment of hematological ...
  • Risk of cancer following an ischemic stroke in the Canadian longitudinal study on aging 

    Rioux, Bastien; Gioia, Laura C.; Keezer, Mark (Cambridge University Press, 2021-03-26)
    Background: Stroke survivors may be at higher risk of incident cancer, although the magnitude and the period at risk remain unclear. We conducted a retrospective cohort study to compare the risk of cancer in stroke survivors to that of the general ...
  • Scoliosis curve type classification from 3D trunk image 

    Adankon, Mathias M.; Dansereau, Jean; Parent, Stefan; Labelle, Hubert; Cheriet, Farida (2012-02-23)
    Adolescent idiopathic scoliosis (AIS) is a deformity of the spine manifested by asymmetry and deformities of the external surface of the trunk. Classification of scoliosis deformities according to curve type is used to plan management of scoliosis ...
  • Sonic hedgehog accelerates DNA replication to cause replication stress promoting cancer initiation in medulloblastoma 

    Tamayo-Orrego, Lukas; Gallo, David; Racicot, Frédéric; Bemmo, Amandine; Mohan, Sushmetha; Ho, Brandon; Salameh, Samer; Hoang, Trang; Jackson, Andrew P.; Brown, Grant W.; Charron, Frédéric (Nature Research, 2020-07-20)
    The mechanisms generating cancer-initiating mutations are not well understood. Sonic hedgehog (SHH) pathway activation is frequent in medulloblastoma (MB), with PTCH1 mutations being a common initiating event. Here we investigated the role of the ...