Parcourir Faculté de médecine – Travaux et publications par sujet "Brain"
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Ammonia toxicity: from head to toe?
(Springer, 2016-12)Ammonia is diffused and transported across all plasma membranes. This entails that hyperammonemia leads to an increase in ammonia in all organs and tissues. It is known that the toxic ramifications of ammonia primarily touch the brain and cause ... -
Ammonia‐lowering strategies for the treatment of hepatic encephalopathy
(Wiley, 2012-08-08)Hyperammonemia leads to neurotoxic levels of brain ammonia and is a major factor involved in the pathogenesis of hepatic encephalopathy (HE). Ammonia‐lowering treatments primarily involve two strategies: inhibiting ammonia production and/or increasing ... -
Identifying the direct effects of ammonia on the brain
(2009-03)Elevated concentrations of ammonia in the brain as a result of hyperammonemia leads to cerebral dysfunction involving a spectrum of neuropsychiatric and neurological symptoms (impaired memory, shortened attention span, sleep-wake inversions, brain ...