Browsing Faculté de médecine – Travaux et publications by Subject "Thymic selection"
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CD5 levels reveal distinct basal T-cell receptor signals in T cells from non-obese diabetic mice
(Wiley, 2021-02-03)Type 1 diabetes in non-obese diabetic (NOD) mice occurs when autoreactive T cells eliminate insulin producing pancreatic β cells. While extensively studied in T-cell receptor (TCR) transgenic mice, the contribution of alterations in thymic selection ...