Browsing Faculté de médecine – Travaux et publications by Subject "Thorough QT study"
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Assessment of the sensitivity of detecting drug-induced QTc changes using subject-specific rate correction
(Elsevier, 2012)Aims To quantify the sensitivity of QT heart-rate correction methods for detecting drug-induced QTc changes in thorough QT studies. Methods Twenty-four-hour Holter ECGs were analyzed in 66 normal subjects during placebo and moxifloxacin delivery ...