Browsing Faculté de médecine – Travaux et publications by Author "Pelletier, Adam-Nicolas"

Now showing items 1-2 of 2

  • The dichotomous pattern of IL-12R and IL-23R expression elucidates the role of IL-12 and IL-23 in inflammation 

    Chognard, Gaëlle; Bellemare, Lisa; Pelletier, Adam-Nicolas; Domínguez Punaro, María de la Cruz; Beauchamp, Claudine; Guyon, Marie-Josée; Charron, Guy; Morin, Nicolas; Sivanesan, Durga; Kuchroo, Vijay; Kuchroo, Vijay; Michnick, Stephen; Chemtob, Sylvain; Rioux, John David; Lesage, Sylvie (Public Library of Science, 2014-02-21)
    IL-12 and IL-23 cytokines respectively drive Th1 and Th17 type responses. Yet, little is known regarding the biology of these receptors. As the IL-12 and IL-23 receptors share a common subunit, it has been assumed that these receptors are co-expressed. ...

  • Evidence of genetic epistasis in autoimmune diabetes susceptibility revealed by mouse congenic sublines 

    Collin, Roxanne; Dugas, Véronique; Pelletier, Adam-Nicolas; Chabot-Roy, Geneviève; Lesage, Sylvie (Springer, 2021-03-23)
    Susceptibility to autoimmune diabetes is a complex genetic trait. Linkage analyses exploiting the NOD mouse, which spontaneously develops autoimmune diabetes, have proved to be a useful tool for the characterization of some of these traits. In a linkage ...