Now showing items 1-4 of 4

  • HIV-1 envelope glycoprotein amino acids signatures associated with clade B transmitted/founder and recent viruses 

    Kafando, Alexis; Martineau, Christine; El-Far, Mohamed; Fournier, Eric; Doualla-Bell, Florence; Serhir, Bouchra; Kazienga, Adama; Sangaré, Mohamed Ndongo; Sylla, Mohamed; Chamberland, Annie; Charest, Hugues; Tremblay, Cécile (MDPI, 2019-11-01)
    Background: HIV-1 transmitted/founder viruses (TF) are selected during the acute phase of infection from a multitude of virions present during transmission. They possess the capacity to establish infection and viral dissemination in a new host. Deciphering ...
  • HIV-1 envelope sequence-based diversity measures for identifying recent infections 

    Kafando, Alexis; Fournier, Eric; Serhir, Bouchra; Martineau, Christine; Doualla-Bell, Florence; Sangaré, Mohamed Ndongo; Sylla, Mohamed; Chamberland, Annie; El-Far, Mohamed; Charest, Hugues; Tremblay, Cécile (Public Library of Science, 2017-12-28)
    Identifying recent HIV-1 infections is crucial for monitoring HIV-1 incidence and optimizing public health prevention efforts. To identify recent HIV-1 infections, we evaluated and compared the performance of 4 sequence-based diversity measures including ...
  • A short-term assessment of nascent HIV-1 transmission clusters among newly diagnosed individuals using envelope sequence-based phylogenetic analyses 

    Kafando, Alexis; Serhir, Bouchra; Doualla-Bell, Florence; Fournier, Eric; Sangaré, Mohamed Ndongo; Martineau, Christine; Sylla, Mohamed; Chamberland, Annie; El-Far, Mohamed; Charest, Hugues; Tremblay, Cécile (Mary Ann Liebert, 2019-10-01)
    The identification of transmission clusters (TCs) of HIV-1 using phylogenetic analyses can provide insights into viral transmission network and help improve prevention strategies. We compared the use of partial HIV-1 envelope fragment of 1,070 bp ...
  • Upregulated IL-32 expression and reduced gut short chain fatty acid caproic acid in people living with HIV with subclinical atherosclerosis 

    El-Far, Mohamed; Durand, Madeleine; Turcotte, Isabelle; Larouche-Anctil, Etienne; Sylla, Mohamed; Zaidan, Sarah; Chartrand-Lefebvre, Carl; Bunet, Rémi; Ramani, Hardik; Sadouni, Manel; Boldeanu, Irina; Chamberland, Annie; Lesage, Sylvie; Baril, Jean-Guy; Trottier, Benoit; Thomas, Réjean; Gonzalez, Emmanuel; Filali-Mouhim, Ali; Goulet, Jean-Philippe; Martinson, Jeffrey A.; Kassaye, Seble; Karim, Roksana; Kizer, Jorge R.; French, Audrey L.; Gange, Stephen J.; Ancuta, Petronela; Routy, Jean-Pierre; Hanna, David B.; Kaplan, Robert C.; Chomont, Nicolas; Landay, Alan L.; Tremblay, Cécile (Frontiers Media, 2021-04-15)
    Despite the success of antiretroviral therapy (ART), people living with HIV (PLWH) are still at higher risk for cardiovascular diseases (CVDs) that are mediated by chronic inflammation. Identification of novel inflammatory mediators with the inherent ...