Hepatitis C Virus seroconversion among persons who inject drugs in relation to primary care physician visiting: The potential role of primary healthcare in a combined approach to Hepatitis C prevention
dc.contributor.author | Artenie, Andreea Adelina | |
dc.contributor.author | Roy, Elise | |
dc.contributor.author | Zang, Geng | |
dc.contributor.author | Jutras-Aswad, Didier | |
dc.contributor.author | Bamvita, Jean-Marie | |
dc.contributor.author | Puzhko, Svetlana | |
dc.contributor.author | Daniel, Mark | |
dc.contributor.author | Bruneau, Julie | |
dc.date.accessioned | 2017-10-22T19:29:26Z | |
dc.date.available | MONTHS_WITHHELD:12 | fr |
dc.date.available | 2017-10-22T19:29:26Z | |
dc.date.issued | 2015-10 | |
dc.identifier.uri | http://hdl.handle.net/1866/19335 | |
dc.publisher | Elsevier | fr |
dc.subject | Hepatitis C | fr |
dc.subject | Drug use | fr |
dc.subject | Injection | fr |
dc.subject | Primary care | fr |
dc.subject | Physician | fr |
dc.subject | Prevention | fr |
dc.title | Hepatitis C Virus seroconversion among persons who inject drugs in relation to primary care physician visiting: The potential role of primary healthcare in a combined approach to Hepatitis C prevention | fr |
dc.type | Article | fr |
dc.contributor.affiliation | Université de Montréal. Faculté de médecine. Département de médecine de famille et médecine d'urgence | fr |
dc.identifier.doi | 10.1016/j.drugpo.2015.04.013 | |
dcterms.abstract | Background: Meaningful reductions in Hepatitis C Virus (HCV) transmission rates among persons who inject drugs (PWID) require a comprehensive prevention approach, including access to harm reduction measures and to healthcare-related interventions, such as HCV screening, testing and antiviral treatment. Little is known, however, about the role of visiting a primary care physician (PCP) in relation to HCV infection risk among PWID, when integrated within a combined prevention approach. This study assessed the association between PCP visiting and HCV seroconversion among PWID attending needle exchange programs (NEP). Methods: A prospective cohort study, HEPCO, was conducted among active PWID in Montréal (2004-2013). Interviews scheduled at three- or six-month intervals included completion of an interviewer-administered questionnaire, and collection of blood samples for HCV antibody testing. HCV-seronegative participants who reported NEP attendance at baseline and had at least one follow-up visit were eligible for this study. HCV incidence was calculated using the person-time method. Time-varying Cox regression modeling was conducted to evaluate the relationship between self-reported recent PCP visiting and HCV incidence. Results: At baseline assessment, of 226 participants (80.5% male; median age: 30.6 years), 37.2% reported having recently visited a PCP. During 449.6 person-years of follow-up, 79 participants seroconverted to HCV [incidence rate: 17.6 per 100 person-years, 95% confidence interval (CI): 14.0-21.8]. Covariate-adjusted analyses indicated that visiting a PCP was associated with a lower risk of HCV infection [Adjusted Hazard Ratio: 0.54, 95% CI: 0.31-0.93]. Other independent predictors of HCV infection included unstable housing, cocaine injection and prescription opioid injection. Conclusion: Among PWID attending NEP, visiting a PCP was associated with a lower risk of HCV infection. Yet, only a minority of participants reported PCP visiting. Efforts to intensify engagement with PCP among PWID could potentially contribute to lower HCV transmission when integrated within a combined approach to prevention. | fr |
dcterms.language | eng | fr |
UdeM.VersionRioxx | Version acceptée / Accepted Manuscript | |
oaire.citationTitle | International journal od drug policy | |
oaire.citationVolume | 26 | |
oaire.citationStartPage | 970 | |
oaire.citationEndPage | 975 |
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