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Mechanistic insights into the directed assembly of hydrogel blocks mediated by polyelectrolytes or microgels
(2017-04-18)
In this study, we report the directed assembly of hydrogel blocks mediated by
electrostatic interactions. We compared two different assembly mechanisms, one
mediated by microgel particles and another mediated ...
Anticorps monoclonaux et immunothérapie : théorie et applications
(2024)
Ce document est une mise à jour d’un précédent publié sur le site Papyrus de l’Université de Montréal en 2023. Il tient compte des cibles thérapeutiques nouvelles ainsi que des anticorps monoclonaux agréés l’an dernier par ...
Monoclonal antibodies and immunotherapy : theory and applications
(2024)
This document is an update of a previous one published on the Papyrus site of the University of Montreal in 2023. It takes into account new therapeutic targets as well as monoclonal antibodies approved last year by the ...
Antiplatelet therapy for atherothrombotic disease in 2022 : from population to patient-centered approaches
(Frontiers Media, 2022-01-28)
Antiplatelet agents, with aspirin and P2Y12 receptor antagonists as major key molecules, are currently the cornerstone of pharmacological treatment of atherothrombotic events including a variety of cardio- and cerebro-vascular ...
Clinical correlates identify ProBDNF and thrombo-inflammatory markers as key predictors of circulating p75NTR extracellular domain levels in older adults
(Frontiers Media, 2022-02-21)
The p75NTR receptor binds all neurotrophins and is mostly known for its role in neuronal survival and apoptosis. Recently, the extracellular domain (ECD) of p75NTR has been reported in plasma, its levels being dysregulated ...
Electrostatic screening length in “soft” electrolyte solutions
(American Chemical Society, 2019-07-30)
Using the Surface Forces Apparatus on solutions of polymeric ions, the effect of specific ion–ion correlations is evaluated on the characteristic decay length, λ, of screened electrostatic interactions between charged ...
Tyrosine-based rivastigmine-loaded organogels in the treatmant of Alzheimer's disease
(2010-08)
Organogels can be prepared by immobilizing an organic phase into a threedimensional
network coming from the self-assembly of a low molecular weight gelator molecule. In this work, an injectable subcutaneous organogel ...
Understanding and diagnosing the potential for bias when using machine learning methods with doubly robust causal estimators
(SAGE, 2018-05-02)
Data-adaptive methods have been proposed to estimate nuisance parameters when using doubly robust semiparametric methods for estimating marginal causal effects. However, in the presence of near practical positivity violations, ...
Resistance and mutations of non-specificity in the field of anxietydepressive disorders in Canadian medical journals, 1950-1990
(Elsevier, 2014-12-03)
Pharmaceuticalisation is a complex phenomenon, co-constitutive of what scholars identify as a pharmaceutical
regime, comprised of networks of actors, institutions and artefacts as well as cognitive
structures that underlie ...
Head‐to‐Head comparison of consensus‐recommended platelet function tests to assess P2Y12 Inhibition : insights for multi‐center trials
(MDPI, 2020)
The vasodilator‐associated stimulated phosphoprotein (VASP) phosphorylation level is a
highly specific method to assess P2Y12 receptor inhibition. Traditionally, VASP phosphorylation is
analyzed by flow cytometry, which ...