Browsing Faculté de pharmacie – Travaux et publications by Subject "Cardiovascular disease"

Now showing items 1-4 of 4

  • Acetylcholinesterase inhibitors and risk of bleeding and acute ischemic events in non-hypertensive Alzheimer’s patients 

    Al-Hamed, ‪Faez Saleh; Kouniaris, Stamatis; Tamimi, Iskandar; Lordkipanidzé, Marie; Madathi, Sreenath Arekunnath; Kezouh, Abbas; Karp, Igor; Nicolau, Belinda; Tamimi, Faleh (2021-08-20)
    Introduction: Acetylcholinesterase inhibitors (AChEIs) are commonly used to treat mild to moderate cases of Alzheimer disease (AD). To the best of our knowledge, there has been no study estimating the risk of bleeding and cardiovascular events in ...

  • Antiplatelet therapy for atherothrombotic disease in 2022 : from population to patient-centered approaches 

    Jourdi, Georges; Godier, Anne; Lordkipanidzé, Marie; Marquis-Gravel, Guillaume; Gaussem, Pascale (Frontiers Media, 2022-01-28)
    Antiplatelet agents, with aspirin and P2Y12 receptor antagonists as major key molecules, are currently the cornerstone of pharmacological treatment of atherothrombotic events including a variety of cardio- and cerebro-vascular as well as peripheral ...

  • Current and novel antiplatelet therapies for the treatment of cardiovascular diseases 

    Jourdi, Georges; Lordkipanidzé, Marie; Philippe, Aurélien; Bachelot-Loza, Christilla; Gaussem, Pascale (MDPI, 2021-12-03)
    Over the last decades, antiplatelet agents, mainly aspirin and P2Y12 receptor antagonists, have significantly reduced morbidity and mortality associated with arterial thrombosis. Their pharmacological characteristics, including pharmacokinetic/pharmacodynamics ...

  • Platelet function in aging 

    Le Blanc, Jessica; Lordkipanidzé, Marie (Frontiers Media, 2019-08-07)
    Aging is associated with an increased incidence of cardiovascular disease and thrombosis. Platelets play a major role in maintaining hemostasis and in thrombus formation, making them a key player in thrombotic disorders. Whereas it is well-known that ...