Now showing items 1-2 of 2

  • Deep tissue penetration of bottle-brush polymers via cell capture evasion and fast diffusion 

    Rabanel, Jean-Michel; Mirbagheri, Marziye; Olszewski, Mateusz; Xie, Guojun; Le Goas, Marine; Latreille, Pierre-Luc; Counil, Hermine; Hervé, Vincent; Oliveira Silva, Rummenigge; Zaouter, Charlotte; Adibnia, Vahid; Acevedo, Mariana; Servant, Marc; Martinez, Vincent A.; Patten, Shunmoogum A.; Matyjaszewski, Krzysztof; Ramassamy, Charles; Banquy, Xavier (American Chemical Society, 2022-12-14)
    Drug nanocarriers (NCs) capable of crossing the vascular endothelium and deeply penetrating into dense tissues of the CNS could potentially transform the management of neurological diseases. In the present study, we investigated the interaction of ...
  • Nanoparticle shell structural cues drive in vitro transport properties, tissue distribution and brain accessibility in Zebrafish 

    Rabanel, Jean-Michel; Faivre, Jimmy; Zaouter, Charlotte; Patten, Shunmoogum A.; Banquy, Xavier; Ramassamy, Charles (Elsevier, 2021-08-24)
    Zwitterion polymers with strong antifouling properties have been suggested as the prime alternative to polyethylene glycol (PEG) for drug nanocarriers surface coating. It is believed that PEG coating shortcomings, such as immune responses and incomplete ...