Browsing Faculté de pharmacie – Travaux et publications by Author "Xie, Guojun"

Now showing items 1-7 of 7

  • Biomimetic bottle-brush polymer coatings for fabrication of ultra-low fouling surfaces 

    Xia, Yinqiang; Adibnia, Vahid; Huang, Renliang; Murschel, Frederic; Faivre, Jimmy; Xie, Guojun; Olszewski, Mateusz; De Crescenzo, Gregory; Qi, Wei; He, Zhimin; Su, Rongxin; Matyjaszewski, Krzysztof; Banquy, Xavier (Wiley, 2018-11-13)
    The increasing demand for long lasting antifouling surfaces has steered the development of accessible, novel, biocompatible and environmentally-friendly materials. Inspired by lubricin (LUB), a component of mammalian synovial fluid with excellent ...

  • Deep tissue penetration of bottle-brush polymers via cell capture evasion and fast diffusion 

    Rabanel, Jean-Michel; Mirbagheri, Marziye; Olszewski, Mateusz; Xie, Guojun; Le Goas, Marine; Latreille, Pierre-Luc; Counil, Hermine; Hervé, Vincent; Oliveira Silva, Rummenigge; Zaouter, Charlotte; Adibnia, Vahid; Acevedo, Mariana; Servant, Marc; Martinez, Vincent A.; Patten, Shunmoogum A.; Matyjaszewski, Krzysztof; Ramassamy, Charles; Banquy, Xavier (American Chemical Society, 2022-12-14)
    Drug nanocarriers (NCs) capable of crossing the vascular endothelium and deeply penetrating into dense tissues of the CNS could potentially transform the management of neurological diseases. In the present study, we investigated the interaction of ...

  • Intermolecular interactions between Bottlebrush Polymers boost the protection of surfaces against frictional wear 

    Faivre, Jimmy; Shrestha, Buddha R.; Xie, Guojun; Olszewski, Mateusz; Adibnia, Vahid; Moldovan, Florina; Montembault, Alexandra; Sudre, Guillaume; Delair, Thierry; David, Laurent; Matyjaszewski, Krzysztof; Banquy, Xavier (ACS Publications, 2018-05-30)
    Polymers exhibiting the bottlebrush (BB) architecture have excellent lubricating properties. However, to motivate their use in real life systems, they must also protect surfaces against frictional damage. In this article, we synthesized a library of ...

  • Lubrication and wear protection of micro-structured hydrogels using bioinspired fluids 

    Faivre, Jimmy; Montembault, Alexandra; Sudre, Guillaume; Shrestha, Buddha R.; Xie, Guojun; Matyjaszewski, Krzysztof; Benayoun, Stéphane; Banquy, Xavier; Delair, Thierry; David, Laurent (American Chemical Society, 2018-11-21)
    We report the fabrication and the use of a bioinspired synovial fluid acting as a lubricant fluid and anti-wear agent at soft and porous chitosan hydrogel tribopairs. This synthetic synovial fluid is composed of sodium hyaluronate (HA) and a bottle-brush ...

  • Synergy between zwitterionic polymers and hyaluronic acid enhances antifouling performance 

    Xia, Yinqiang; Adibnia, Vahid; Shan, Cancan; Huang, Renliang; Qi, Wei; He, Zhimin; Xie, Guojun; Olszewski, Mateusz; De Crescenzo, Gregory; Matyjaszewski, Krzysztof; Banquy, Xavier; Su, Rongxin (American Chemical Society, 2019-09-03)
    Challenges associated with nonspecific adsorption of proteins on sensor surfaces have steered the development of novel antifouling materials and strategies. Inspired by human synovial fluid composition and structure, we designed synergistic antifouling ...

  • Unraveling the correlations between conformation, lubrication, and chemical stability of bottlebrush polymers at interfaces 

    Faivre, Jimmy; Shrestha, Buddha R.; Xie, Guojun; Delair, Thierry; David, Laurent; Matyjaszewski, Krzysztof; Banquy, Xavier (American Chemical Society, 2017-09-29)
    In the present study, we monitored the conformation and chemical stability of a hydrophilic bottlebrush (BB) polymer in pure water and buffered saline solutions. We correlated these parameters to lubricating and wear protecting properties. Using the ...

  • Wear protection without surface modification using a synergistic mixture of molecular brushes and linear polymers 

    Faivre, Jimmy; Shrestha, Buddha R.; Burdynska, Joanna; Xie, Guojun; Moldovan, Florina; Delair, Thierry; Benayoun, Stéphane; David, Laurent; Matyjaszewski, Krzysztof; Banquy, Xavier (American Chemical Society, 2017-01-10)
    We describe the design of lubricating and wear protecting fluids based on mixtures of bottlebrushes (BB) and linear polymers solutions. To illustrate this concept we used hyaluronic acid (HA) - a naturally occurring linear polyelectrolyte, and a water ...