Browsing Faculté de pharmacie – Travaux et publications by Author "Wang, Guanbo"
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Estimating treatment importance in multidrug-resistant tuberculosis using Targeted Learning : an observational individual patient data network meta-analysis
Estimating MDR-TB treatment importance using TMLE
Wang, Guanbo; Schnitzer, Mireille; Menzies, Dick; Viiklepp, Piret; Holtz, Timothy H.; Benedetti, Andrea (Wiley, 2019)Persons with multidrug‐resistant tuberculosis (MDR‐TB) have a disease resulting from a strain of tuberculosis (TB) that does not respond to at least isoniazid and rifampicin, the two most effective anti‐TB drugs. MDR‐TB is always treated with multiple ... -
Modeling treatment effect modification in multidrug-resistant tuberculosis in an individual patient data meta-analysis
Liu, Yan; Schnitzer, Mireille; Wang, Guanbo; Kennedy, Edward; Viiklepp, Piret; Vargas, Mario H.; Sotgiu, Giovanni; Menzies, Dick; Benedetti, Andrea (SAGE, 2021)Effect modification occurs while the effect of the treatment is not homogeneous across the different strata of patient characteristics. When the effect of treatment may vary from individual to individual, precision medicine can be improved by identifying ...