Browsing Faculté de pharmacie – Travaux et publications by Author "Bolzinger, Marie-Alexandrine"

Now showing items 1-2 of 2

  • Effect of surface chemistry of polymeric nanoparticles on cutaneous penetration of cholecalciferol 

    Lalloz, Augustine; Bolzinger, Marie-Alexandrine; Faivre, Jimmy; Latreille, Pierre-Luc; García Ac, Araceli; Rakotovao, Cyrielle; Rabanel, Jean-Michel; Hildgen, Patrice; Banquy, Xavier; Briançon, Stéphanie (Elsevier, 2018-10-11)
    We investigated the influence of nanoparticle (NP) surface composition on different aspects of skin delivery of a lipophilic drug: chemical stability, release and skin penetration. Cholecalciferol was chosen as a labile model drug. Poly(lactic acid) ...

  • Subtle and unexpected role of PEG in tuning the penetration mechanisms of PLA-based nano-formulations into intact and impaired skin 

    Lalloz, Augustine; Bolzinger, Marie-Alexandrine; Briançon, Stéphanie; Faivre, Jimmy; Rabanel, Jean-Michel; García Ac, Araceli; Hildgen, Patrice; Banquy, Xavier (Elsevier, 2019-02-27)
    We present a systematic study of the role of poly(ethylene glycol) (PEG) content in NPs on drug skin absorption. Cholecalciferol-loaded NPs of 100 nm of diameter were prepared by flash nanoprecipitation from PLA-b-PEG copolymers of various PEG lengths. ...